CRUETZFEDLT-JAKOB DISEASE CREUTZFELDTJAKOB DISEASE. What is Creutzfeldt-Jakob disease? Creutzfeldt-Jakob disease (CJD) is a rare, fatal brain disorder caused by a prion. http://www.idph.state.il.us/public/hb/hbcjdhlb.htm
Extractions: CREUTZFELDT-JAKOB DISEASE What is Creutzfeldt-Jakob disease? Creutzfeldt-Jakob disease (CJD) is a rare, fatal brain disorder caused by a prion. The disease causes mental deterioration and a variety of neurological symptoms, and usually leads to death within a year of onset. Threre are various forms of CJD; in about 85 percent of the cases, the cause is unknown. One form of CJD may be linked to consumption of beef in Great Britain. Another form is familial or genetic, that is, relatives of a CJD case with the form are more likely to develop the disease than other persons. Many Americans first heard of the disease in 1983 when they learned it had claimed the life of New York City Ballet choreographer George Balanchine. How does CJD affect the patient? In early stages of the disease, patients may experience failing memory, changes in behavior, lack of coordination or visual disturbances. As the illness progresses, mental deterioration becomes pronounced, involuntary movements (especially muscle jerks) appear, and the patient may become blind, develop weakness in the arms or legs, and ultimately lapse into a coma. Death is usually due to infections in the bedridden, unconscious patient. Symptoms of CJD can be similar to those seen in other progressive neurological disorders such as Alzheimer's disease and other dementias. However, CJD causes unique changes in brain tissue that, at this time, can be detected only by surgical biopsy or at autopsy.
Creutzfeldt-Jakob Disease: Symptoms - MayoClinic.com CreutzfeldtJakob disease — Comprehensive overview covers definition, symptoms and diagnosis of CJD. http://www.mayoclinic.com/health/creutzfeldt-jakob-disease/DS00531/DSECTION=symp
Extractions: zWASL=1;zGRH=1 zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zDO=0 Home Health Alzheimer's Disease Search From Christine Kennard , former About.com Guide Updated: November 30, 2006 About.com Health's Disease and Condition content is reviewed by the Medical Review Board Alzheimer's Basics Types of Dementia zSB(3,3) Creutzfeldt-Jakob disease (CJD) is a very rare dementing disease first identified in the 1920s. Creutzfeldt-Jakob disease is believed to be caused by something called proteinaceous prions that can live in the body for years before any signs of the disease become obvious. CJD affects people between the ages of 50 and 70 years. Creutzfeldt-Jakob disease is a rapid, progressive neurological disease that can affect people and animals. In animals these prion diseases are also known as Scrapie in sheep, bovine spongiform encephalopathy (BSE) also known as mad cow disease found in cattle. A similar disease is also found in deer. New variant Creutzfeldt-Jakob disease (vCJD)
Alzheimer's Association - Creutzfeldt-Jakob Disease CreutzfeldtJakob disease (CJD) (pronounced CROYZ-felt YAH-cob) is a rare, rapidly fatal disorder affecting about 1 out of 1 million people per year worldwide. http://www.alz.org/alzheimers_disease_creutzfeldt_Jakob_disease.asp
Extractions: Creutzfeldt-Jakob disease (CJD) (pronounced CROYZ-felt YAH-cob ) is a rare, rapidly fatal disorder affecting about 1 out of 1 million people per year worldwide. It usually affects individuals older than 60. CJD is one of the prion ( PREE-awn ) diseases. These diseases occur when prion protein, which is present throughout the brain, begins to assume an abnormal three-dimensional shape. This shape gradually triggers the protein throughout the brain to fold into the same abnormal shape, leading to increasing damage and destruction of brain cells. Recently, “variant Creutzfeldt-Jakob disease (vCJD)” was identified as the human disorder believed to be caused by eating meat from cattle affected by “mad cow disease.” It tends to occur in much younger individuals, in some cases as early as their teens. The first symptoms may involve impairment in memory, thinking and reasoning or changes in personality and behavior.
UK Creutzfeldt-Jakob Disease Surveillance Unit The incidence of CreutzfeldtJakob disease (CJD) is monitored in the UK by the National CJD Surveillance Unit (NCJDSU) based at the Western General Hospital in Edinburgh, Scotland. http://www.cjd.ed.ac.uk/
Extractions: The National Creutzfeldt-Jakob Disease Surveillance Unit (NCJDSU) The incidence of Creutzfeldt-Jakob disease (CJD) is monitored in the UK by the National CJD Surveillance Unit (NCJDSU) based at the Western General Hospital in Edinburgh, Scotland. The Unit brings together a team of clinical neurologists, neuropathologists and scientists specialising in the investigation of this disease. This document is intended to summarise the research in progress at the NCJDSU and also provide some background information about CJD and other human spongiform encephalopathies. We have also provided some links to other resources and contrary points of view available on the Web. Figures for the number of CJD cases and referrals of suspected cases of CJD to the NCJDSU since 1990. NCJDSU protocol for CJD surveillance across the UK. National Referral System . From July 2004, a new national reporting system was announced by the Chief Medical Officer . This is centred on the National CJD Reporting Form to be faxed, by the notifying clinician, to the National Creutzfeldt-Jakob Disease Surveillance Unit (NCJDSU), the National Prion Clinic (NPC) and the local CCDC.
Extractions: In this section: Introduction Creutzfeldt-Jakob Disease Lewy body Dementia Frontotemporal Dementia ... Vascular Dementia Related page: What Is Alzheimer's Disease? Alzheimer's disease is the most common of a large group of disorders known as "dementias." It is an irreversible disease of the brain in which the progressive degeneration of brain cells causes thinking ability and memory to deteriorate. Alzheimer's disease also affects behaviour, mood and emotions, and the ability to perform daily living activities. There is currently no cure for Alzheimer's disease, but there are treatment options and lifestyle choices that can slow its progression and, within the next five years, treatments are expected that may well stop the disease in its tracks! Also, the pursuit of new research strategies should one day help restore some lost function and memory. Alzheimer's disease progresses through early, middle and late stages before reaching the final end of life stage. However, identifying the transition from one stage to another is often difficult. Not only does the disease usually progress slowly, but the symptoms related to each stage tend to overlap and the order in which they appear and how long they last varies from person to person.
Creutzfeldt-Jakob Disease / Family Village CreutzfeldtJakob Disease. Who to Contact; Where to Go to Chat with Others; Learn More About It; Web Sites; Search Google for Creutzfeldt-Jakob Disease http://www.familyvillage.wisc.edu/lib_cjd.htm
WHO | Variant Creutzfeldt-Jakob Disease Variant CreutzfeldtJakob disease. Variant Creutzfeldt-Jakob disease (vCJD) is a rare and fatal human neurodegenerative condition. As with Creutzfeldt-Jakob disease, vCJD is http://www.who.int/mediacentre/factsheets/fs180/en/
Extractions: Revised November 2002 Variant Creutzfeldt-Jakob disease (vCJD) is a rare and fatal human neurodegenerative condition. As with Creutzfeldt-Jakob disease, vCJD is classified as a Transmissible Spongiform Encephalopathy (TSE) because of characteristic spongy degeneration of the brain and its ability to be transmitted. vCJD is a new disease that was first described in March 1996. Before the identification of vCJD, CJD was recognized to exist in only three forms. Sporadic cases, which have an unknown cause and occur throughout the world at the rate of about one per million people, account for 85–90% of CJD cases. Familial cases are associated with a gene mutation and make up 5–10% of all CJD cases. Iatrogenic cases result from the accidental transmission of the causative agent via contaminated surgical equipment or as a result of cornea or dura mater transplants or the administration of human-derived pituitary growth hormones. Less than 5% of CJD cases are iatrogenic. In contrast to the traditional forms of CJD, vCJD has affected younger patients (average age 29 years, as opposed to 65 years), has a relatively longer duration of illness (median of 14 months as opposed to 4.5 months) and is strongly linked to exposure, probably through food, to a TSE of cattle called Bovine Spongiform Encephalopathy (BSE).
Creutzfeldt-Jakob Disease (pathology) -- Britannica Online Encyclopedia CreutzfeldtJakob disease (pathology), rare fatal degenerative disease of the central nervous system. Creutzfeldt-Jakob disease occurs throughout the world at an incidence of http://www.britannica.com/EBchecked/topic/142824/Creutzfeldt-Jakob-disease
Extractions: document.write(''); Search Site: With all of these words With the exact phrase With any of these words Without these words Home My Britannica CREATE MY Creutzfeldt-... NEW ARTICLE ... SAVE Table of Contents: Creutzfeldt-Jakob disease Article Article Year in Review Links Year in Review Links Related Articles Related Articles External Web sites External Web sites Citations ARTICLE from the Creutzfeldt-Jakob disease rare fatal degenerative disease of the central nervous system . Creutzfeldt-Jakob disease occurs throughout the world at an incidence of one person in a million; however, among certain populations, such as Libyan Jews, rates are somewhat higher. The disease commonly occurs in adults between the ages of 40 and 70, although some young adults have been stricken with the disease. Both men and women are affected equally. The onset of the disease is usually characterized by vague psychiatric or behavioral changes, which are followed within weeks or months by a progressive dementia that is often accompanied by abnormal vision and involuntary movements. There is no known cure for the disease, which is usually fatal within a year of the onset of symptoms.
Disease Information From NORD, National Organization For Rare Disorders, Inc. National Organization for Rare Disorders is dedicated to helping people with rare, orphan diseases. Rarediseases.org contains information on the prevention, treatment and cure http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Creutzfeldt J
Introduction To CJD Introduction. CreutzfeldtJakob disease (CJD) is a rare and fatal neurodegenerative disease of unknown cause. Patients are usually aged between 50 and 75 and typical clinical http://www.cjd.ed.ac.uk/intro.htm
Extractions: Introduction Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative disease of unknown cause. Patients are usually aged between 50 and 75 and typical clinical features include a rapidly progressive dementia associated, myoclonus and a characteristic electroencephalographic pattern. Neuropathological examination reveals cortical spongiform change, hence the term `spongiform encephalopathy'. H.G. Creutzfeldt is credited with the first description of the disorder in 1920, although by current diagnostic criteria his case would be highly atypical. A year later another German neurologist, A. Jakob, described four cases, at least two of whom had clinical features suggestive of the entity we recognise as CJD. Aetiology The nature of the transmissible agent is the matter of some controversy. Previously considered a `slow virus' no viral agent has ever been convincingly demonstrated and no evidence of an immunological response seen. Additionally the infectious pathogen shows a remarkable resistance to treatments that would normally be expected to inactivate viruses. The viral hypothesis has been elegantly challenged by the prion (` pro teinaceous in Epidemiology The majority of cases are sporadic (85%), between 10-15% are familial and the remainder are iatrogenic.
Extractions: *National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA; National Creutzfeldt-Jakob Disease Surveillance Unit, Western General Hospital, Edinburgh, Scotland; Central Veterinary Laboratory, New Haw, Addlestone, UK; Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland, USA; Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Robbinsville, New Jersey, USA The epidemic of bovine spongiform encephalopathy in the United Kingdom, which began in 1986 and has affected nearly 200,000 cattle, is waning to a conclusion, but leaves in its wake an outbreak of human Creutzfeldt-Jakob disease, most probably resulting from the consumption of beef products contaminated by central nervous system tissue. Although averaging only 10-15 cases a year since its first appearance in 1994, its future magnitude and geographic distribution (in countries that have imported infected British cattle or cattle products, or have endogenous BSE) cannot yet be predicted. The possibility that large numbers of apparently healthy persons might be incubating the disease raises concerns about iatrogenic transmissions through instrumentation (surgery and medical diagnostic procedures) and blood and organ donations. Government agencies in many countries continue to implement new measures to minimize this risk.
Creutzfeldt-Jakob Disease (www.whonamedit.com) CreutzfeldtJakob disease A very rare, progressive syndrome of motor, sensory, and mental disturbances, involving the cerebral cortex, basal ganglia and spinal cord. Also http://www.whonamedit.com/synd.cfm/696.html
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Creutzfeldt-Jakob Disease - Definition Of Creutzfeldt-Jakob Disease In The Medic CreutzfeldtJakob Disease Definition. Creutzfeldt-Jakob disease (CJD) is a transmissible, rapidly progressing, neurodegenerative disorder called a spongiform degeneration related to http://medical-dictionary.thefreedictionary.com/Creutzfeldt-Jakob disease
!site_name The UCSF Memory and Aging Center is a medical clinic and research center dedicated to understanding, diagnosing and treating CreutzfeldtJakob disease (CJD) around the world. http://memory.ucsf.edu/cjd/
Creutzfeldt-Jakob Disease CreutzfeldtJakob Disease Some documents on this page are saved in the Portable Document Format (PDF). http://www.health.state.ny.us/diseases/communicable/creutzfeldt-jakob/fact_sheet
Extractions: skip to main content Information for a Healthy New York Search this site: Some documents on this page are saved in the Portable Document Format (PDF). If it's not already on your computer, you'll need to download the latest free version of Adobe Reader You are Here: Home Page Alzheimer's Disease and Other Dementias Creutzfeldt-Jakob Disease Last Reviewed: November 2006 Creutzfeldt-Jakob disease, often referred to as CJD, is a rare, fatal disease affecting the nervous system. CJD most frequently occurs in people between 55 and 75 years old. For 80 to 90 percent of the people diagnosed with CJD, scientists do not know the cause. These individuals are referred to as having sporadic CJD. Between 5 percent and 15 percent of CJD cases are genetic, meaning the risk for the disease is inherited. These individuals are referred to as having familial CJD. Finally, in less than 1 percent of all cases, CJD is caused by direct exposure to tissue contaminated with CJD through specific types of medical procedures involving nervous system tissue.
