41. Behçet's Syndrome - MEDSTUDENTS - RHEUMATOLOGY Although there is no invariable feature of Beh et’s disease, certain features occur often enough to constitute a definable syndrome and serve as the basis for diagnostic criteria http://www.medstudents.com.br/reumat/reumat3.htm

RHEUMATOLOGY VANESSA FONSECA LORENA DE ARAÚJO, MD Medstudents' Homepage Behçet's Syndrome Definition and Diagnostic Criteria Behçet’s syndrome is a multisystem disorder presenting with recurrent oral and/or genital ulcerations, chronic relapsing uveitis that may cause blindness and neurologic impairments. Although there is no invariable feature of Behçet’s disease, certain features occur often enough to constitute a definable syndrome and serve as the basis for diagnostic criteria. The diagnostic criteria established by the International Study Group for Behçet’s disease requires the presence of recurrent oral ulceration, in the absence of other clinical explanations, and two of the following: recurrent genital ulceration, eye lesions, skin lesions and/or a pathergy test (table I) . The pathergy test is the pustular reaction of the skin in response to intradermal needle prick. This nonspecific skin inflammatory reactivity denotes increased neutrophil chemotaxis and was once thought to be pathognomonic of Behçet’s disease. However, this reaction occurs in no more than 70% of the patients, usually in those with more extensive disease. Clinical Manifestations The recurrent oral ulcers are a sine qua non for the diagnosis. The ulcers are usually painful, are round or oval, are 2 to 10 mm in diameter, are shallow or deep with a central yellowish necrotic base, are found anywhere in the oral cavity and may appear singly or in crops, which is more common. These ulcers persist for 1 to 2 weeks and subside without leaving scars. The genital ulcers resemble the oral ones, however, isolated genital ulcers are seldom indicative of Behçet’s disease. While vaginal ulcers are usually painless, those on the external genitalia may be painful.

42. Behcets Disease An essay or paper on Behcets Disease. Hulusi Behcet, a Turkish dermatologist first described a disease associating uveitis with genital and oral aphthous lesions, a disease http://www.lotsofessays.com/viewpaper/1708825.html

var base_url = "http://www.lotsofessays.com/"; Arts Business Custom Research Economics ... Login Behcets Disease Hulusi Behcet, a Turkish dermatologist first described a disease associating uveitis with genital and oral aphthous lesions, a disease which now bears his name in 1937 (Wechsler and Piette 1199). Fifty years later, Behcet's disease had expanded and was recognized as a chronic, multisystem disorder in which vasculitis was the underlying disorder. The disease occurs in the second to fourth decade of life, and rarely in children and adults over the age of 50 years. During the annual meeting of the Medical Society of Athens in 1930, Benediktos Adamantiades, a Greek ophthalmologist from Prussa in Asia Minor, which is now Bursa, Turkey, gave a lecture on a case of "relapsing iritis with hypopyon" and described a case of a young man with three cardinal signs of the disease (Zouboulis and Kaklomanis 691). He connected the symptoms of genital ulcers , arthritis, and ocular disease as manifestations of a single disease entity, and correlated it with the findings of others. In 1946, Adamantiades added thrombophlebitis as a fourth sign of the disease, and later presented the first classification of the disease, describing the ocular, mucocutaneous and systemic forms. This has led to the adoption of the term Adamantiades-Behcet's disease, since it honors both men who first described the disease and its manifestations. The etiology of Behcet's disease is not really known (Wechsler and Piette 1199). There may be an infectious cause, with suggestions ranging from streptococci to her

43. Arthritis Research & Therapy | Full Text | Behcet's Disease Shunsei Hirohata and Hirotoshi Kikuchi. Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan http://arthritis-research.com/content/5/3/139

44. BBC - Health: Behcet's Disease BBC Behcet's disease Behcet's syndrome is a disorder with recurrent ulcers and inflammation. http://www.bbc.co.uk/health/physical_health/conditions/behcets1.shtml

gloader.load(["glow", "1", "glow.anim", "glow.net", "glow.dom", "glow.embed"]); BBC.adverts.write("leaderboard",true); BBC.adverts.show("leaderboard"); British Broadcasting Corporation Home Accessibility links Skip to content Skip to local navigation Skip to bbc.co.uk navigation Skip to bbc.co.uk search ... Support Behcet's disease Dr Rob Hicks Behcet's disease is a rare autoimmune disorder that causes ulcers and skin lesions and is often wrongly assumed to be sexually transmitted. Dr Rob Hicks last medically reviewed this article in November 2007 On this page What causes it? What are the symptoms? Who's affected? How is it diagnosed? ... Advice and support Page options Print this page What causes it? Behcet's disease, an autoimmune response where the immune system turns on the body, causes inflammation of parts of the body. In particular, small blood vessels around the body become inflamed, a condition known as vasculitis. The cause of Behcet's remains unknown, but it's often preceded by a viral infection, for example, which may trigger the autoimmune process, causing the body to attack its own blood vessels and making them inflamed. Experts in the field of Behcet's research agree the causes may be genetic. Life for people with Behcet's is made more difficult because of misunderstandings about the illness. With the appearance of ulcers on the mouth and genitals, it's often incorrectly assumed the condition is infectious and sexually transmitted - it's not either of these.

45. Behcet's Disease: Symptoms And Treatment In Behcet's Disease Behcet's is a chronic autoimmune disorder characterized by vasculitis, oral and genital ulcers, and uveitis, which can occur in patients with hepatitis C. http://www.suite101.com/content/behcet-s-disease-a5087

46. Behcet's Disease - Symptoms, Treatment And Prevention of Behcet's Disease; Causes and Risk Factors of Behcet's Disease......Symptoms, Treatment and Prevention of Behcet's Disease Definition of Behcet's Disease; http://www.healthscout.com/ency/68/645/main.html

47. Behcet's Disease - Behcet's Disease Of The Eye Behcet's disease often affects the eye. http://vision.about.com/od/eyediseasesandconditions/g/Behcets.htm

zWASL=1;zGRH=1 zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zDO=0 Home Health Vision Vision Search Vision Healthy Eyes Eye Problems Vision Correction ... Share w(x2+zWl+'?p=1" zT="18/1[N" rel="nofollow">Print') Free Vision Newsletter! Sign Up Discuss in my Forum By Troy Bedinghaus, O.D. , About.com Guide Updated January 10, 2008 About.com Health's Disease and Condition content is reviewed by the Medical Review Board See More About: eye cancer diseases of the eye Definition: An autoimmune disease that results from damage to blood vessels throughout the body. It is thought to be caused by an autoimmune reaction that causes the blood vessels to become inflamed. The disease is named after Hulusi Behcet, a Turkish dermatologist and scientist. Four symptoms are usually associated with the disease including sores inside the mouth, sores on the genitals, inflammation inside the eye, and skin problems. Other symptoms may include arthritis, blood clots, and inflammation of the digestive tract and central nervous system. Behcet's disease is not contagious, and tends to affect more men than women. The disease is most common in the Middle East, Asia and Japan. Behcet's is rare in the United States. Also Known As: Behcet's syndrome, Adamantiades, silk road disease

48. Behcet Disease. DermNet NZ Behcet disease. Authoritative facts about the skin from the New Zealand Dermatological Society. http://dermnetnz.org/systemic/behcet.html

@import url("/common/screen.css"); DermNet NZ Advertisement Facts about skin from the New Zealand Dermatological Society Incorporated . Topic index: A B C D ... Skin signs and systemic disease Behcet disease What is Behcet disease? Behcet disease is a rare disease characterised by painful mouth ulcers, genital ulcers, eye problems and skin lesions. The disease is named after the Turkish dermatologist Hulusi Behcet who first described the syndrome in 1924. What causes Behcet disease? The cause of Behcet disease is unknown but it is presumed to be an autoimmune disorder. This is where an individual's immune system starts reacting against his or her own tissues. The reason for this remains a mystery but it is possible bacterial or viral infection may have a role in its development. Who is at risk of Behcet disease? Behcet disease is most common and more serious in people with Silk Road bloodlines. Silk Road countries include those in the Mediterranean basin, Middle East and Far East; the incidence is around 1 in 10,000 people. However, Behcet disease is seen worldwide even in those with other ethnic heritage; in the US the incidence is reported to be 1 in 20,000. In people with Silk Road ancestry, Behcet disease is more common in men than in women. However, the trend is reversed with more women than men being affected in people of other ethnic origins. The disease can develop at any age but is most common as people reach 20-30 years.

49. Rheumatology Therapeutics Medical Center What Is Beh et's Disease? The disease was first described in 1937 by Dr. Helusi Beh et, a professor of http://www.arthritisconsult.com/behcetsdisease.html

See More Information on this Topic WebMD http://www.WebMD.com http://www.behcets.com/ YAHOO http://www.Yahoo.com The Arthritis Foundation http://www.arthritis.org/ The National Institute of Arthritis and Musculoskeletal and Skin Diseases 877-22-NIAMS http://www.nih.gov/niams/ American College of Rheumatology http://www.rheumatology.org/ American Autoimmune Related Diseases Association, Inc., http://www.aarda.org/ ConsumerLab http://www.consumerlab.com Mouth sores Genital sores Uveitis (yoo.vee.EYE.tis) Arthritis Vasculitis -This is an inflammation of blood vessels and can cause small strokes, severe skin ulcers (called pathergy), mouth or genital ulcers, of rupture of large blood vessels in the lung, chest, or abdomen. Skin Problems Blood Clots Central Nervous System Digestive Tract Mouth sores at least three times in 12 months Any two of the following symptoms: recurring genital sores, eye inflammation with loss of vision, skin lesions, or positive pathergy (skin prick test).

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