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  1. Chronic neurological diseases: Subacute Sclerosing Panencephalitis, progressive multifocal Leukoencephalopathy, Kuru, Creutzfeldt-Jakob Disease by Jacob A Brody, 1976

1. Creutzfeldt–Jakob Disease - Wikipedia, The Free Encyclopedia
Creutzfeldt–Jakob disease or CJD is a degenerative neurological disorder (brain disease) that is incurable and invariably fatal. It is the most common among the types of
http://en.wikipedia.org/wiki/Creutzfeldt–Jakob_disease
Creutzfeldt–Jakob disease
From Wikipedia, the free encyclopedia Jump to: navigation search This article's introduction section may not adequately summarize its contents . To comply with Wikipedia's lead section guidelines , please consider expanding the lead to provide an accessible overview of the article's key points. (July 2009) Creutzfeldt–Jakob disease Classification and external resources
Tonsil biopsy in variant CJD. Prion Protein immunostaining. ICD A F ICD ... MeSH Creutzfeldt–Jakob disease or CJD (pronounced /ˈkrɔɪtsfɛlt ˈjɑːkoʊb/ "KROITS-felt YA-kob") is a degenerative neurological disorder brain disease ) that is incurable and invariably fatal. It is the most common among the types of transmissible spongiform encephalopathy found in humans.
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2. Creutzfeldt-Jakob Disease
CreutzfeldtJakob disease Definition Creutzfeldt-Jakob disease (CJD) is a form of brain damage that leads to a rapid decrease of mental function and movement.
http://adam.about.com/encyclopedia/infectiousdiseases/Creutzfeldt-Jakob-disease.

3. Creutzfeldt-Jakob Disease Fact Sheet: National Institute Of Neurological Disorde
CreutzfeldtJakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. It affects about one person in every one million people
http://www.ninds.nih.gov/disorders/cjd/detail_cjd.htm
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Table of Contents (click to jump to sections)
What is Creutzfeldt-Jakob Disease?
What are the Symptoms of the Disease?

How is CJD Diagnosed?

What Causes Creutzfeldt-Jakob Disease?
...
How is the Disease Treated?
What is Creutzfeldt-Jakob Disease?
Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. It affects about one person in every one million people per year worldwide; in the United States there are about 200 cases per year. CJD usually appears in later life and runs a rapid course. Typically, onset of symptoms occurs about age 60, and about 90 percent of individuals die within 1 year. In the early stages of disease, people may have failing memory, behavioral changes, lack of coordination and visual disturbances. As the illness progresses, mental deterioration becomes pronounced and involuntary movements, blindness, weakness of extremities, and coma may occur. There are three major categories of CJD:
  • In sporadic CJD, the disease appears even though the person has no known risk factors for the disease. This is by far the most common type of CJD and accounts for at least 85 percent of cases.

4. Creutzfeldt Jakob Disease
Important It is possible that the main title of the report Creutzfeldt Jakob Disease is not the name you expected. Please check the synonyms listing to find the alternate name
http://www.webmd.com/brain/creutzfeldt-jakob-disease

5. Creuzfeldt-Jakob Disease - CJD Foundation
The Creutzfeldt Jakob Foundation offers support, information and guidance to those dealing with the degenerative neurological disorder CJD.
http://www.cjdfoundation.org/
Toll-Free 1.800.659.1991
site map
other resources contact us

Your browser does not support inline frames or is currently configured not to display inline frames. Welcome to the Creutzfeldt-Jakob Disease Foundation Website. This site contains information compiled with the needs of CJD patients and their families in mind. The CJD Foundation consists of members who want to support you through this experience. Support is a key ingredient in coping with CJD. Support from those who have had similar experiences can be more helpful than any written information. The primary goal of the CJD Foundation is to be part of your support system. The CJD Foundation is also concerned about the complexity of issues surrounding this brain disease. Our philosophy is to be proactive by establishing collaborations and linkages, communicating with family members, researchers, physicians and political representatives and informing the broader community about CJD. Our HelpLine is available. Calls are answered during work hours Monday-Friday 9:00 am-5:00 pm Eastern Time. Calls concerning patient issues that are received after business hours are returned in the evenings and on weekends. Please call us at 1.800.659.1991

6. Creutzfeldt-Jakob Disease - Definition Of Creutzfeldt-Jakob Disease By The Free
Creutz feldtJa kob disease (kroits f lt-y k p) n. A rare, usually fatal disease of the brain, characterized by progressive dementia and gradual loss of muscle control
http://www.thefreedictionary.com/Creutzfeldt-Jakob disease

7. Creutzfeldt-Jakob Disease Information Page: National Institute Of Neurological D
CreutzfeldtJakob Disease (CJD) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
http://www.ninds.nih.gov/disorders/cjd/cjd.htm
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Condensed from Creutzfeldt-Jakob Disease Fact Sheet
Table of Contents (click to jump to sections)
What is Creutzfeldt-Jakob Disease?
Is there any treatment?

What is the prognosis?

What research is being done?
...
Additional resources from MEDLINEplus
What is Creutzfeldt-Jakob Disease?
Is there any treatment?
There is no treatment that can cure or control CJD. Current treatment is aimed at alleviating symptoms and making the patient as comfortable as possible. Opiate drugs can help relieve pain, and the drugs clonazepam and sodium valproate may help relieve involuntary muscle jerks.
What is the prognosis?

8. Creutzfeldt-Jakob Disease Foundation - CJD Information
CJD INFORMATION CreutzfeldtJakob Disease Introduction Prion diseases are a group of rare, invariably fatal brain disorders which occur both in humans and certain animals.
http://www.cjdfoundation.org/cjdisease.html
CJD INFORMATION
Creutzfeldt-Jakob Disease Introduction
Prion diseases are a group of rare, invariably fatal brain disorders which occur both in humans and certain animals. They first came to public attention in the mid 1980s in the form of the BSE epidemic in the United Kingdom. BSE (bovine spongiform encephalopathy) is a prion disease in cattle. Tissue from infected animals may have contaminated cattle feed, leading to the silent spread of the BSE epidemic. There is also a theory that BSE came from feed contaminated with scrapie, the long established sheep prion disease. Inevitably, concern over whether BSE could pass to humans mounted.
In humans the best known of the prion diseases is Creutzfeldt-Jakob Disease (CJD), which reportedly affects around one person per million per year. In the United States this translates to 250-300 new cases per year. It is well known that CJD is very difficult to diagnose leading to speculation that the one case per million report may be incorrect. Most of the cases are "classical" or "sporadic" CJD (sCJD), occurring for no, as yet, known reason. The sporadic form accounts for approximately 85% of the cases, the familial form approximately 15%. There have also been a few cases which have occurred from contamination via medical procedures; this type is known as iatrogenic or Acquired CJD. Finally over the last few years, another type of Acquired CJD called variant (vCJD) has been identified in young people. vCJD has been linked to ingestion of beef tainted with BSE (bovine spongiform encephalopathy), most cases have occurred in the United Kingdom.

9. Creutzfeldt-Jakob Disease - MayoClinic.com
CreutzfeldtJakob disease — Comprehensive overview covers definition, symptoms and diagnosis of CJD.
http://www.mayoclinic.com/health/creutzfeldt-jakob-disease/DS00531

10. Creutzfeldt-Jakob Disease | LIVESTRONG.COM
CreutzfeldtJakob disease CJD is a form of brain damage that causes a rapid decrease of mental function and movement. Transmissible spongiform encephalopathy vCJD CJD Jacob
http://www.livestrong.com/creutzfeldt-jakob-disease/

11. Creutzfeldt-Jakob Disease: MedlinePlus Medical Encyclopedia
CreutzfeldtJakob disease (CJD) is a form of brain damage that leads to a rapid decrease of mental function and movement. Causes
http://www.nlm.nih.gov/medlineplus/ency/article/000788.htm
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Creutzfeldt-Jakob disease
Creutzfeldt-Jakob disease (CJD) is a form of brain damage that leads to a rapid decrease of mental function and movement.
Causes
CJD is believed to result from a protein called a prion. A prion causes normal proteins to fold abnormally. This affects the other proteins' ability to function. There are several types of CJD. The disorder is very rare, occurring in about 1 out of 1 million people. It usually first appears between ages 20 and 70, with average age at onset of symptoms in the late 50s. CJD can be grouped into classic or new variant disease. The classic types of CJD are:
  • Sporadic CJD makes up the majority of cases. It occurs for no known reason. Average age at onset is 65 Familial CJD results when a person inherited the abnormal prion (inherited CJD is rare)
Classic CJD is not related to mad cow disease (bovine spongiform encephalitis However, new variant CJD (nvCJD) is an infectious form that

12. Variant Creutzfeldt-Jakob Disease And Bovine Spongiform Encephalopathy: EMedicin
Overview Bovine spongiform encephalopathy (BSE), also known as mad cow disease, and variant CreutzfeldtJakob disease (CJD) are related disorders. They belong to the family of
http://emedicine.medscape.com/article/1169688-overview

13. CREUTZFELDT JAKOB DISEASE
CREUTZFELDT JAKOB DISEASE SEE STEADY INCREASE IN SPORADIC CJD IN THE USA FROM 1997 TO 2006. SPORADIC CJD CASES TRIPLED, with phenotype of 'UNKNOWN' strain growing.
http://creutzfeldt-jakob-disease.blogspot.com/
var BL_backlinkURL = "http://www.blogger.com/dyn-js/backlink_count.js";var BL_blogId = "37789475";
CREUTZFELDT JAKOB DISEASE
SEE STEADY INCREASE IN SPORADIC CJD IN THE USA FROM 1997 TO 2006. SPORADIC CJD CASES TRIPLED, with phenotype of 'UNKNOWN' strain growing. ... http://www.cjdsurveillance.com/resources-casereport.html
Wednesday, October 27, 2010
A novel variant of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report
A novel variant of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report
BMC Neurology 2010, 10:99 doi:10.1186/1471-2377-10-99
Ana B Rodriguez (abrodriguez@neiker.net)
Joseba M Garrido (jgarriod@neiker.net)
Juan J Zarranz (juanjose.zarranzimirizaldu@osakidetza.net)
Jose M Arteagoitia (vigipro1-san@ej-gv.es)
Marian Martinez de Pancorbo (marianpancorbo@gmail.com)
Begona Atares (M.BEGONA.ATARESPUEYO@osakidetza.net)
Miren J Bilbao (MIRENJOSU.BILBAOARTECHE@osakidetza.net)
Isidro Ferrer (8082ifa@gmail.com)

14. Creutzfeldt-Jakob Disease
CreutzfeldtJakob disease. Creutzfeldt-Jakob disease is a disease of bizarre nature. There is a very small amount of information that has been available to the embalming profession
http://psyweb.com/Mdisord/Dementia/CJdisease.jsp

15. Creutzfeldt-Jakob Disease (CJD) Causes, Symptoms, And Treatment On
Learn about CreutzfeldtJakob disease (CJD) symptoms such as progressive dementia, insomnia, dperssion, and unusual sensations.
http://www.medicinenet.com/creutzfeldt-jakob_disease/article.htm
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What is Creutzfeldt-Jakob Disease?
Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. It affects about one person in every one million people per year worldwide; in the United States there are about 200 cases per year. CJD usually appears in later life and runs a rapid course. Typically, onset of symptoms occurs about age 60, and about 90 percent of patients die within 1 year. In the early stages of disease, patients may have failing

16. Creutzfeldt-Jakob Disease Information On Healthline
CreutzfeldtJakob disease (CJD) is a form of brain damage that leads to a rapid decrease of mental function and movement.
http://www.healthline.com/adamcontent/creutzfeldt-jakob-disease

17. Creutzfeldt-Jakob Disease: MedlinePlus
CreutzfeldtJakob disease (CJD) is a rare, degenerative brain disorder . Symptoms usually start around age 60. Memory problems, behavior changes, vision problems and poor
http://www.nlm.nih.gov/medlineplus/creutzfeldtjakobdisease.html
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Creutzfeldt-Jakob Disease
URL of this page: http://www.nlm.nih.gov/medlineplus/creutzfeldtjakobdisease.html Also called: CJD Creutzfeldt-Jakob disease (CJD) is a rare, degenerative brain disorder . Symptoms usually start around age 60. Memory problems, behavior changes, vision problems and poor muscle coordination progress quickly to dementia , coma and death. Most patients die within a year. The three main categories of CJD are
  • sporadic CJD, which occurs for no known reason hereditary CJD, which runs in families acquired CJD, which occurs from contact with infected tissue, usually during a medical procedure
Cattle can get a disease related to CJD called bovine spongiform encephalopathy (BSE) or "mad cow disease." There is concern that people can get a variant of CJD from eating beef from an infected animal, but there is no direct proof to support this. NIH: National Institute of Neurological Disorders and Stroke Creutzfeldt-Jakob disease (CJD) is a rare, degenerative brain disorder. Symptoms usually start around age 60. Memory problems, behavior changes, vision problems and poor muscle coordination progress quickly to dementia, coma and death. Most patients die within a year.

18. Creutzfeldt-Jakob Disease (CJD) Definition - Medical Dictionary
Online Medical Dictionary and glossary with medical definitions
http://www.medterms.com/script/main/art.asp?articlekey=2863

19. CDC - Creutzfeldt-Jakob Disease, Classic (CJD)
This tissue slide shows spongelike lesions in the brain tissue of a classic CJD patient. This lesion is typical of many prion diseases.
http://www.cdc.gov/ncidod/dvrd/cjd/
@import url('http://www.cdc.gov/css/global.css'); @import url('/ncezid/local/b/css/local.css'); Home About CDC Press Room Funding ... Contact Us Search: CJD (Creutzfeldt-Jakob Disease, Classic)
About CJD
This tissue slide shows sponge-like lesions in the brain tissue of a classic CJD patient. This lesion is typical of many prion diseases. Larger Picture
(Image courtesy Ermias Belay) Classic CJD is a human prion disease. It is a neurodegenerative disorder with characteristic clinical and diagnostic features. This disease is rapidly progressive and always fatal. Infection with this disease leads to death usually within 1 year of onset of illness. Important Note: Classic CJD is not related to "mad cow" disease. Classic CJD also is distinct from "variant CJD", another prion disease that is related to BSE. For information about these diseases, see:
Occurrence and Transmission
Classic CJD has been recognized since the early 1920s. The most common form of classic CJD is believed to occur sporadically, caused by the spontaneous transformation of normal prion proteins into abnormal prions. This sporadic disease occurs worldwide, including the United States, at a rate of approximately one case per 1 million population per year, although rates of up to two cases per million are not unusual. The risk of CJD increases with age, and in persons aged over 50 years of age, the annual rate is approximately 3.4 cases per million. In recent years, the United States has reported fewer than 300 cases of CJD a year.

20. Creutzfeldt-Jakob Disease - House Wiki
CreutzfeldtJakob disease (CJD) is a brain wasting disease. The best evidence is that it is caused by a malformed protein that interferes with the repair and operation of
http://house.wikia.com/wiki/Creutzfeldt-Jakob_disease
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          Creutzfeldt-Jakob disease
          Edit Read more: Diseases Creutzfeldt-Jakob disease Pathology Type Protein transmitted illness ( prion disease Cause(s) Ingestion of infected brain material, typically cow brains Symptoms Delirium personality change, Gait Mortality Rate Inevitably fatal Treatments Palliative Show Information [Source] Creutzfeldt-Jakob disease (CJD) is a brain wasting disease. The best evidence is that it is caused by a malformed protein that interferes with the repair and operation of existing brain tissue. It appears to be related to Mad Cow disease and scrapie, both of which cause similar symptoms in cows and sheep respectively. Brains of Creutzfeldt patients on autopsy are riddled with holes. The mode of transmission of the disease is believed to be consumption of meat contaminated by brain tissue. Prions can apparently survive heating, so cooking does not appear to affect transmission of the disease. However, vegetarians have also been known to have developed the disease. The disease is very rare, even in countries where Mad Cow disease is known.

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