61. Huntington's Disease Huntington's disease (HD) was described by George Huntington (18501916) who was born in Long Island, New York. He described this disorder in his only known written article http://www.netdoctor.co.uk/diseases/facts/huntingtons.htm

Advertisement Advertisement Home Site map Follow us on Facebook Follow us on twitter ... Weight loss programme Seniors' health Your health Arthritis Coping with Parkinson's disease Stress urinary incontinence (SUI) ... What is a sight test for? Advertisement Home Seniors' health Your health Huntington's disease Written by Dr Linda Appai-Kubi , King's College Hospital and Guy's King's ST. Thomas's School of Medicine, London and Dr K Ray Chaudhuri , King's College Hospital and Guy's King's ST. Thomas's School of Medicine, London What is Huntington's disease? Huntington's disease (HD) was described by George Huntington (1850-1916) who was born in Long Island, New York. He described this disorder in his only known written article called 'on chorea'. Huntington's disease is a genetic disorder (inherited due to a faulty gene) which usually affects people in their 40s and 50s. It primarily affects the brain, with a gradual loss of control of movement, memory and mental ability. HD is also associated with personality changes and depression as well as other mental illnesses. There is currently no cure for HD, although many strategies may be used to improve the quality of life for sufferers and their carers.

62. BBC - Health: Huntington's Disease BBC Huntington's disease Living with Huntington's disease Huntington's disease is a hereditary disorder that damages the nerve cells of certain areas of the brain. http://www.bbc.co.uk/health/physical_health/conditions/huntingtons1.shtml

gloader.load(["glow", "1", "glow.anim", "glow.net", "glow.dom", "glow.embed"]); BBC.adverts.write("leaderboard",true); BBC.adverts.show("leaderboard"); British Broadcasting Corporation Home Accessibility links Skip to content Skip to local navigation Skip to bbc.co.uk navigation Skip to bbc.co.uk search ... Support Huntington's disease Dr Rob Hicks Dr Trisha Macnair Huntington's disease is a hereditary disorder that damages the nerve cells of certain areas of the brain. Dr Trisha Macnair last medically reviewed this article in March 2009. On this page What is Huntington's disease Symptoms Causes and risk factors Treatment and recovery ... Advice and support Page options Print this page What is Huntington's disease Huntington's disease (also referred to in more formal medical research as Huntington Disease) is an hereditary neurological disorder of the central nervous system that causes progressive degeneration of cells in the brain, slowly impairing a person's ability to walk, think, talk and reason. It was first described in 1872 by an American doctor, George Huntington, who studied an extended family in Long Island affected by the condition. Top Symptoms Symptoms develop gradually over months or years. The age at which they first appear is usually between about 30 and 50.

63. Neuroscience For Kids - In The News - Huntington's Disease Huntington's Disease By Ellen Kuwana Neuroscience for Kids Staff Writer January 11, 2001. Basic Facts about Huntington's Disease http://faculty.washington.edu/chudler/hunting.html

A Glimmer of Hope for Huntington's Disease Patients By Ellen Kuwana Neuroscience for Kids Staff Writer January 11, 2001 Basic Facts about Huntington's Disease Results from two research groups provide hope to the people who battle against Huntington's disease (HD). HD is a relatively rare disease, affecting approximately 30,000 people in the US. HD is an inherited neurological disorder: if either parent has it, his or her child has a 50-50 chance of getting it. Symptoms, which usually appear after age 30, include dementia, chorea (jerky, random movements of the body), poor coordination, depression, memory loss and mood swings. Although there are a few drugs that help with the symptoms, there is no treatment for HD and patients often die within 15 years of the onset of symptoms. Inside the HD Brain HD damages neurons in the area of the brain called the basal ganglia, especially the caudate nucleus and globus pallidus. What if there was a way to replace these damaged brain cells? Using rodent and primate models of Huntington's disease, researchers have taken fetal brain cells, transplanted them into brains damaged by HD, and shown that the transplanted cells survive. Would this technique work in humans and if the cells survived, would they do the jobs that the damaged cells previously did such as form connections, relay signals, and secrete neurotransmitters? First Time Transplanted Fetal Cells Survive and Improve HD Symptoms in Humans Marc Peschanski and colleagues harvested fetal neurons from the area that was destined to develop into the striatum and transplanted these cells into the striatum of adult patients with mild to moderate HD. These patients had exhibited symptoms of HD for two to seven years. The scientists then evaluated the patients one year later with

64. Huntington's Disease. [Lancet. 2007] - PubMed Result PubMed is a service of the U.S. National Library of Medicine that includes over 19 million citations from MEDLINE and other life science journals for biomedical articles back http://www.ncbi.nlm.nih.gov/pubmed/17240289

65. Genetic Testing For Huntington's Disease A Guide for Families G enetic Testing for Huntington's Disease Huntington's Disease Society of America New York, New York Print version published with funding from the http://www.lkwdpl.org/hdsa/hdtest.htm

A Guide for Families G enetic Testing for Huntington's Disease Huntington's Disease Society of America New York, New York Print version published with funding from the Bess Spiva Timmons Foundation. Online version reprinted with permission. Original text by Marilyn J. Wolff Contents I. Huntington's Disease and the HD Gene What is Huntington's Disease (HD)? How do I know if I am at risk for HD? Can I get HD in any other way? If I was born with the gene, then why don't I have HD now? Has the gene for HD been identified? How does this gene work? If all people have the gene for HD, why do only some develop the disease? II. Genetic Testing How can I be tested? What does presymptomatic testing entail? Should I bring a friend with me? Are blood samples from my family members necessary for testing? How much does it cost? Will health insurance pay for testing? Are the results of the test always accurate? Are the test results confidential? If the test results cannot tell me when the disease will begin, how will I know if I am beginning to show symptoms? Should I be tested for HD?

66. Genetics Of Huntington's Disease Genetics of Huntington disease. Debra Collins, M.S., CGC Genetic Counselor Division of Endocrinology, Metabolism and Genetics University of Kansas Medical Center http://www.kumc.edu/hospital/huntingtons/genetics.html

Genetics of Huntington disease Debra Collins, M.S., CGC Genetic Counselor Division of Endocrinology, Metabolism and Genetics University of Kansas Medical Center Huntington disease (HD) is a genetic disorder of the central nervous system with symptoms usually appearing in adults within the third or fourth decade of life, although symptoms can occur in individuals younger or older than this. Within the same family, the symptoms vary both in their rate of progression and in the age of onset. Symptoms may include involuntary movements and loss of motor control. In addition, personality changes may occur, with loss of memory and decreased mental capacity. Symptoms in individuals, as well as confirmation of diagnosis in other family members, are used to determine the diagnosis. Huntington disease is inherited as an autosomal dominant condition. The human body contains 100 trillion cells. A nucleus is inside each human cell (except red blood cells). Each nucleus contains 46 chromosome arranged in 23 pairs. One chromosome of every pair is from each parent. The chromosome are filled from each tightly coiled strands of DNA. Genes are segments of DNA that contain instructions to make proteins and other building blocks of life. An affected parent passes either the HD gene, or the other working gene, to their off spring. There is a 50% (1 in 2) chance at each pregnancy that a child of an affected parent will receive the gene for Huntington disease. The age of onset, degree and type of clinical symptoms, as well as rate of progression varies with HD.

67. Huntington's Disease | The Human Genome Huntington's disease 27/1/04. By Richard Twyman A progressive neurodegenerative disorder that usually strikes in middle to late adult life. http://genome.wellcome.ac.uk/doc_WTD020863.html

68. Huntington's Disease << Types Of Illnesses And Disabilities << Illnesses And Dis Additional Resources; Huntington's disease (HD) is a disorder in which certain nerve cells in your brain die. It is caused by a single defective gene. http://www.womenshealth.gov/illness-disability/types-illness-disability/huntingt

Skip Navigation Skip left navigation Illnesses and Disabilities Home Types of Illnesses and Disabilities ... womenshealth.gov Home Illnesses and Disabilities Illnesses and Disabilities E-mail this page to a friend Home Illnesses and Disabilities Types of Illnesses and Disabilities Huntington's Disease Choose an illness or disability: Accident (Unintentional Injury) Alcoholism and Drug Addiction Alzheimer's Disease Amputation Arthritis Asperger Syndrome Attention Deficit Hyperactivity Disorder Autism Bipolar Disorder Burn Injury Cancer Celiac Disease Cerebral Palsy Charcot-Marie-Tooth Disease Chronic Fatigue Syndrome Chronic Obstructive Pulmonary Disease (COPD) Crohn's Disease Cystic Fibrosis Dementia Depression Diabetes Dissociative Disorder Down Syndrome Dwarfism Eating Disorders Epilepsy Fetal Alcohol Spectrum Disorders Fibromyalgia Generalized Anxiety Disorder Hearing Loss and Deafness Heart Disease

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