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         Human Genome Project:     more books (100)
  1. The Human Genome Project and the Future of Health Care (Medical Ethics)
  2. The Human Genome Project: Webster's Timeline History, 1977 - 2007 by Icon Group International, 2009-02-23
  3. Guide to the Human Genome Project: Technologies, People, And Information (Chemical Heritage Foundation Publication, No. 11) by Susan L. Speaker; M. Susan Lindee; Elizabeth Hanson, 2003-06-01
  4. Bibliography: Ethical legal & social implications of the Human Genome Project by Michael S Yesley, 1993
  5. The Human Genome Project by Thomas F. Lee, 1991-08-21
  6. Human Genome Project: An entry from Macmillan Reference USA's <i>Macmillan Reference USA Science Library: Genetics</i> by Ralph R. Meyer, 2003
  7. Perilous Knowledge: Human Genome Project and Its Implications by Tom Wilkie, 1994-09-16
  8. The Human Genome Project
  9. Human Genome Project - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Health Publica Icon Health Publications, 2004-01-05
  10. The Human Genome Project (Health and Your Body) by James Toriello, 2009-01
  11. Genomics: The Science and Technology Behind the Human Genome Project by Charles R. Cantor, Cassandra L. Smith, 1999-02-02
  12. The Human Genome Project and Minority Communities: Ethical, Social, and Political Dilemmas
  13. Scientific Feuds: From Galileo to the Human Genome Project by Joel Levy, 2010-10-05
  14. The Book of Man: The Human Genome Project and the Quest to Discover Our Genetic Heritage by Sir Walter Bodmer, Robin McKie, 1997-08-21

21. NOVA Online | Cracking The Code Of Life | Nature Vs Nurture Revisited
After a decade of hype surrounding the Human Genome Project, punctuated at regular intervals by gaudy headlines proclaiming the discovery of genes for killer diseases and complex
http://www.pbs.org/wgbh/nova/genome/debate.html
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The news that shocked the world: We have only about twice as many genes as your average fruit fly. Nature vs Nurture Revisited
by Kevin Davies
The most shocking surprise that emerged from the full sequence of the human genome earlier this year is that we are the proud owners of a paltry 30,000 genes barely twice the number of a fruit fly.
After a decade of hype surrounding the Human Genome Project, punctuated at regular intervals by gaudy headlines proclaiming the discovery of genes for killer diseases and complex traits, this unexpected result led some journalists to a stunning conclusion. The seesaw struggle between our genes nature and the environment nurture had swung sharply in favor of nurture. "We simply do not have enough genes for this idea of biological determinism to be right," asserted Craig Venter, president of Celera Genomics, one of the two teams that cracked the human genome last February. [For a conversation with Venter, see Meet the Decoders
Indeed, Venter has wasted little time in playing down the importance of the genes he has catalogued. He cites the example of colon cancer, which is often associated with a defective "colon cancer" gene. Even though some patients carry this mutated gene in every cell, the cancer only occurs in the colon because it is triggered by toxins secreted by bacteria in the gut. Cancer, argues Venter, is an environmental disease. Strong support for this viewpoint appeared last year in the

22. Pharmacogenomics: Medicine And The New Genetics
Overview, anticipated benefits, and links to related resources. From the U.S. Human Genome Project.
http://www.ornl.gov/sci/techresources/Human_Genome/medicine/pharma.shtml
Human Genome Project Information Genomic Science Program DOE Microbial Genomics home ... Disorders
Pharmacogenomics Basic Information
FAQs

Glossary

Acronyms

Links
...
Media Guide
About the Project
What is it?

Goals

Landmark Papers

Sequence Databases
... FAQs the New Genetics Home Gene Testing Gene Therapy Pharmacogenomics ... Genetic Counseling Ethical, Legal, Social Issues Home Privacy Legislation Gene Testing Gene Therapy ... Human Migration Education Teachers Students Careers Webcasts ... Genética Websites en Español Research Home Sequence Databases Landmark Papers Insights Publications Chromosome Poster Primer Molecular Genetics List of All Publications Search This Site Contact Us Privacy Statement Site Stats and Credits Site Map Quick Links to questions and answers on this page:
What is pharmacogenomics?
Pharmacogenomics is the study of how an individual's genetic inheritance affects the body's response to drugs. The term comes from the words pharmacology and genomics and is thus the intersection of pharmaceuticals and genetics.

23. CellNEWS
Blog on the human genome project, ethics debate, molecular biology, and stem cells.
http://cellnews-blog.blogspot.com/
Pages
Friday, 29 October 2010
Is the Shape of a Genome as Important as Its Content?
Study shows structure exposes genes to regulation and chromosomal crosstalk
Friday, 29 October 2010
The laboratory of Ken-ichi Noma, Ph.D., an assistant professor at the Wistar Institute, has produced the first detailed structure of the fission yeast genome. The researchers demonstrate how the physical structure of the genome itself helps cells regulate and control gene expression. Credit : Ken-ichi Noma, Ph.D./The Wistar Institute. If there is one thing that recent advances in genomics have revealed, it is that our genes are interrelated, "chattering" to each other across separate chromosomes and vast stretches of DNA. According to researchers at The Wistar Institute, many of these complex associations may be explained in part by the three-dimensional structure of the entire genome. A given cell's DNA spends most of its active lifetime in a tangled clump of chromosomes, which positions groups of related genes near to each other and exposes them to the cell's gene-controlling machinery. This structure, the researchers say, is not merely the shape of the genome, but also a key to how it works.
Their study, published online as a featured article in the journal Nucleic Acids Research, is the first to combine microscopy with advanced genomic sequencing techniques, enabling researchers to literally see gene interactions. It is also the first to determine the three-dimensional structure of the fission yeast genome, S. pombe. Applying this technique to the human genome may provide both scientists and physicians a completely new framework from which to better understand genes and disease, the researchers say.

24. Introduction - The Human Genome Project
Introduction The Human Genome Project National Center for Human Genome Research, National Institutes of Health. New Tools for Tomorrow's Health Research.
http://www.accessexcellence.org/RC/AB/IE/Intro_The_Human_Genome.php

25. Human Genome Project - Human DNA Sequence - DNA Sequencing
In 1990, a project was initiated to determine the entire sequence of DNA making up the human genome. The human genome project involved participants from laboratories worldwide
http://biotech.about.com/od/casestudies/a/humangenome.htm
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  • Home Biotech / Biomedical
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    By Theresa Phillips , About.com Guide
    See More About:
    zSB(3,3) The human genome project was initiated in 1990 by the US Department of Energy (DOE) and National Institutes of Health (NIH). It also involved hundreds of scientists from different organizations worldwide. The primary goal of this DNA sequencing project was to determine the entire sequence of nucleotide bases (DNA) in humans (the human genome). In addition to DNA sequencing, the project goals included identifying all of the genes in the human genome, developing and improving techniques for gene sequencing and genomic data analysis and sharing the data and technologies with the private sector. A portion of the money raised for the project was used to address ethical, legal and social issues (ELSI) arising from having determined the genome sequence. This aspect of the project made it unique in that it was the first time a project included evaluation of ELSI arising from its own data.

    26. Genetics Education Center
    Resources for educators interested in human genetics and the human genome project. The site is maintained by Medical Genetics, University of Kansas Medical Center.
    http://www.kumc.edu/gec/
    Genetics Education Center
    University of Kansas Medical Center For educators interested in human genetics and the human genome project Human Genome Project Resources (books, videos, curricula) Lesson Plans Networking Genetic Conditions Careers ... Search The Human Genome Project

    27. Human Genome Project Guide | Genome Project | Human Health
    Guide to Human Genome Project Human Genome Project News, Genome Project Photos, Human Health Articles Blogs
    http://humangenomeproject.info/
    Human Genome Project
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    CONTACT US SITE MAP HUMAN GENOME PROJECT NEWS ... ABOUT US
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    New Sites: Supernatural Photography Bargain Scrapbooks Challenge Workshop Virtual Pets ... Coral Adventures HumanGenomeProject.info Sunday, October 31, 2010
    What's new at Human Genome Project All There is, is dust in the wind; Dust Particulate Traveling The Globe Dust from Deserts and Particulate ControlThe greatest contributor to particulate matter, which effects human health comes from the World? Deserts. In the Western US we have huge deserts. Dust storms from China? deserts have traveled around the World... (read more) The Plight of Industrialized Man Living in the Pacific Northwest is a challenge for any body: the poor excuse for weather west of the Cascades is one of the worst on earth for human health... (read more) Boost the Immune System the Natural Way Since Dr Peter Koeppel, one of the leading experts on immunology and biochemistry at a leading Swiss pharmaceutical company released a paper on the use of nucleotides and RNA for human health applications... (read more) Glyconutrients - The Next Household Word?

    28. The Human Genome Project (Stanford Encyclopedia Of Philosophy)
    The century that opened with rediscoveries of Gregor Mendel's studies on patterns of inheritance in peas closed with a research project in molecular biology heralded as the
    http://plato.stanford.edu/entries/human-genome/
    Cite this entry Search the SEP Advanced Search Tools ...
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    The Human Genome Project
    First published Wed Nov 26, 2008 The official date of completion was timed to coincide with celebrations of the 50 th st This article provides a brief history of the HGP and discusses a range of associated issues that gained the attention of philosophers during the project's planning stages and as it unfolded. Prominent among philosophical concerns are the conceptual foundations of the project and its ethical implications.

    29. ELSI - Human Genome Project
    Primarily a collection of links to sites exploring the ELSI.
    http://www.kumc.edu/gec/prof/geneelsi.html
    Professional policy papers Ethical, Legal, Public Policy Testing / Insurance / Privacy / Nondiscrimination Health Insurance Portability ... Other
    Policy papers on specific issues, professional societies
  • American Society of Human Genetics (ASHG) policy papers on Maternal Serum Alpha-Fetoprotein Screening, DNA Analysis, Cystic Fibrosis, Genetics and Adoption, Cystic Fibrosis Carrier Screening. Genetic Testing for Breast and Ovarian Cancer, Testing in Children and Adolescents, Apolipoprotein E Testing for Alzheimer Disease, Disclosure of Familial Genetic Information, Eugenics, and other Genetic Testing Issues , other policy sites American College of Medical Genetics (ACMG) policy papers on Prenatal FISH Studies, Multiple Marker Screening in Women 35 and Older, Fragile X Syndrome Testing, Advanced Paternal Age, Apolipoprotein E Testing for Alzheimer Disease, Testing in Children and Adolescents, Testing for Prader-Willi and Angelman Syndromes, Population Screening for BRCA-1 Mutation in Ashkenazi Jewish Women, Principles of Screening, Carrier Testing for Canavann Disease , Genetic Testing for Cystic Fibrosis, and other testing issues German Society for Human Genetics Statements and Declarations and Position Paper American Society of Gene Therapy policy / position statements American Academy of Pediatrics genetic policy statements Congenital Adrenal Hyperplasia , Evaluation of the Newborn with Developmental Anomalies of the External Genitalia , Folic Acid for the Prevention of
  • 30. The Human Genome Project
    The Human Genome Project . Electron micrograph of chromosomes, condensed DNA that comprises an organism's genome. By the late 1980s, a fairly large amount of information on
    http://www.ocf.berkeley.edu/~edy/genome/
    Main Menu

    31. JGI - Human Genome Project
    The Human Genome Project is an international effort to discover all of the estimated 30,000-40,000 human genes and make them accessible for further biological study.
    http://www.jgi.doe.gov/science/hgp.html
    Home MyJGI Contact Us Site Map ... Emergency Info JGI website People
    Human Genome Project
    The Human Genome Project (HGP) was an international 13-year effort formally begun in October 1990 to discover all the estimated 30,000-40,000 human genes and make them accessible for further biological study. Another project goal was to determine the complete sequence of the 3 billion DNA subunits (bases in the human genome). As part of the HGP, parallel studies have been carried out on selected model organisms such as the bacterium E. coli to help develop the technology and interpret human gene function. The DOE Human Genome Program and the NIH National Human Genome Research Institute (NHGRI) together made up the U.S. Human Genome Project. JGI's effort in this landmark project went toward sequencing human chromosomes 5, 16, and 19. The assemblies of Chromosomes 5 , and are available on the Genome Portal
    Mapping Data
    Looking for a Cosmid/BAC
    The best way to obtain CIT (CalTech) clones is to order directly from Research Genetics , part of the Invitrogen corporation.

    32. Human Genome Project
    SCOPE NOTE 17 Bioethics Research Library The Joseph and Rose Kennedy Institute of Ethics Box 571212, Georgetown University Washington, DC 200571212
    http://bioethics.georgetown.edu/publications/scopenotes/sn17.htm
    SCOPE
    NOTE
    Bioethics Research Library
    The Joseph and Rose Kennedy Institute of Ethics
    Box 571212, Georgetown University
    Washington, DC 20057-1212
    202-687-3885; fax: 202-687-8089
    e-mail:bioethics@georgetown.edu
    http://bioethics.georgetown.edu
    Human Genome Project
    Table of Contents

    First published in December 1991, Scope Note 17 is an annotated bibliography with links to electronic texts and/or sites where possible. It is updated on a periodic basis. Last updated: July 2010 Introduction To commemorate the 50th anniversary of the discovery of DNA's structure, the human genome sequence and the Human Genome Project were declared complete on April 14, 2003. Using the "working draft" announced on February 12, 2001 (see Science: Human Genome Special Issue ), scientists from around the world (the International Human Genome Sequencing Consortium ) put draft fragments in order so that researchers could use the data "out of the box" without additional sequencing. "If you are looking for a disease gene, you can be confident that it exists in one continuous stretch of highly accurate sequence," said Dr. Francis Collins, director of the genome center at the U.S. National Institutes of Health (III. Wade 2003)

    33. Genome Glossary
    Indexed and cross-referenced collection of genetic s terminology.
    http://www.ornl.gov/sci/techresources/Human_Genome/glossary/index.shtml
    Human Genome Project Information Genomic Science Program DOE Microbial Genomics home ... Research Archive
    Genome Glossary
    Basic Information
    FAQs

    Glossary

    Acronyms

    Links
    ...
    Media Guide
    About the Project
    What is it?

    Goals

    Landmark Papers

    Sequence Databases
    ...
    FAQs
    the New Genetics Home Gene Testing Gene Therapy Pharmacogenomics ... Genetic Counseling Ethical, Legal, Social Issues Home Privacy Legislation Gene Testing Gene Therapy ... Human Migration Education Teachers Students Careers Webcasts ... Genética Websites en Español Research Home Sequence Databases Landmark Papers Insights Publications Chromosome Poster Primer Molecular Genetics List of All Publications Search This Site Contact Us Privacy Statement Site Stats and Credits Site Map A glossary of genetic terms from the DOE Human Genome Program. Choose terms by using the list of links below Also visit the Human Genome Project Information web : what the project is; its progress, history, and goals; what issues are associated with genome research; frequently asked questions, the science behind the project; and who its sponsors are. A B C D ... All Terms (printable version; long download time)

    34. Human Genome - Wikipedia, The Free Encyclopedia
    Personal genomes had not been sequenced in the Human Genome Project to protect the identity of volunteers who provided DNA samples. That sequence was derived from the DNA of
    http://en.wikipedia.org/wiki/Human_genome
    Human genome
    From Wikipedia, the free encyclopedia Jump to: navigation search For a non-technical introduction to the topic, see Introduction to genetics A graphical representation of the normal human karyotype This article needs additional citations for verification
    Please help improve this article by adding reliable references . Unsourced material may be challenged and removed (September 2009) The human genome is the genome of Homo sapiens , which is stored on 23 chromosome pairs. Twenty-two of these are autosomal chromosome pairs , while the remaining pair is sex-determining . The haploid human genome occupies a total of just over 3 billion DNA base pairs . The Human Genome Project (HGP) produced a reference sequence of the euchromatic human genome, which is used worldwide in biomedical sciences The haploid human genome contains ca. 23,000 protein-coding genes , far fewer than had been expected before its sequencing. In fact, only about 1.5% of the genome codes for proteins , while the rest consists of non-coding RNA genes, regulatory sequences introns , and (controversially named) "junk" DNA
    Contents

    35. Gary Schneider
    Genetic Self-Portrait. Photographic installation of fourteen works addressing some of the revolutionary discoveries that were emerging from the Human Genome Project.
    http://museum.icp.org/museum/exhibitions/schneider/

    36. The Human Transcript Map
    T he Human Genome Project is expected to produce a sequence of DNA representing the functional blueprint and evolutionary history of the human species.
    http://www.ncbi.nlm.nih.gov/SCIENCE96/
    A Gene Map of the Human Genome
    An update to this work has been released.
    See GeneMap'99
    T he Human Genome Project is expected to produce a sequence of DNA representing the functional blueprint and evolutionary history of the human species. However, only about 3% of this sequence is thought to specify the portions of our 50,000 to 100,000 genes that encode proteins. Thus an important part of basic and applied genomics is to identify and localize these genes in a process known as transcript mapping. When genes are expressed, their sequences are first converted into messenger RNA transcripts, which can be isolated in the form of complementary DNAs (cDNAs). Approximately half of all human genes had been sampled as of 15 June, 1996. A small portion of each cDNA sequence is all that is needed to develop unique gene markers, known as sequence tagged sites or STSs, which can be detected in chromosomal DNA by assays based on the polymerase chain reaction (PCR). To construct a transcript map, cDNA sequences from a master catalog of human genes were distributed to mapping laboratories in North America, Europe, and Japan. These cDNAs were converted to STSs and their physical locations on chromosomes determined on one of two radiation hybrid (RH) panels or a yeast artificial chromosome (YAC) library containing human genomic DNA. This mapping data was integrated relative to the human genetic map and then cross-referenced to cytogenetic band maps of the chromosomes. (Further details are available in the accompanying article in the 25 October issue of SCIENCE).

    37. Genomics And Its Impact On Science And Society: 2003 Primer
    A primer on basic genetics; the science of the Human Genome Project; genomic medicine; ethical, legal, and social issues; and post-genomics research - from the U.S. Dept. of Energy Human Genome Program.
    http://www.ornl.gov/sci/techresources/Human_Genome/publicat/primer2001/index.sht
    Genomics and Its Impact on Science and Society The Human Genome Project and Beyond
    a publication of the U.S. Department of Energy Human Genome Program June 2008 Use the buttons to navigate between chapters and the button to return to this table of contents. This document is also available in printer-friendly PDF format , viewable with Adobe Acrobat. Powerpoint slides are available to accompany this Primer. Genomics 101: A Primer The Human Genome Project: 1990-2003 Insights from the Human DNA Sequence Medicine and the New Genetics ... Dictionary of Genetic Terms Search This Report:
    This document may be cited in the following style:
    Human Genome Program, U.S. Department of Energy, Genomics and Its Impact on Science and Society: A 2008 Primer For printed copies, please complete this form . Send questions or comments to martinsa@ornl.gov . Author is Denise K. Casey. Site designed by Marissa Mills.
    The online presentation of this publication is a special feature of the Human Genome Project Information Web site Document Use and Credits
    Publications and webpages on this site were created by the U.S. Department of Energy Genome Program's

    38. Human Genome Project
    Human Genome Project Concise synopsis of its history, ultimate goal, and implications that suggests we should proceed wisely and cautiously with this knowledge.
    http://www.allaboutpopularissues.org/human-genome-project.htm
    Human Genome Project
    - Let's Move Carefully You are here: Popular Issues Human Genome Project Human Genome Project - What is it?
    The Human Genome Project, comprised of the U.S. Department of Energy and NIH Human Genome Programs, is the national coordinated effort to characterize all human genetic material by determining the complete sequence of DNA in the human genome. The Human Genome Project's ultimate goal is to discover and map all of the approximately 35,000 human genes and make them accessible for further biological study. To facilitate the future interpretation of human gene function, the Human Genome Project is also conducting parallel studies on the genetic makeup of other organisms. Human Genome Project - The DNA Sequence Has Been Revealed
    After years of multi-billion-dollar research, the Human Genome Project and Celera Genomics (a non-government biotechnology company) jointly announced drafts of the human genome sequence in 2000. By mid-2001, scientists associated with these ventures had presented the true nature and complexity of the digital code inherent in DNA. We now understand that there are approximately 35,000 genes in each human DNA molecule, comprised of approximately 3 billion chemical bases arranged in precise sequence. Even the DNA molecule for the single-celled bacterium, E. coli

    39. Human Genome Project | The Human Genome
    The Human Genome Project is the largest international collaboration ever undertaken in biology. Between 1990 and 2003, thousands of scientists worldwide undertook the immense
    http://genome.wellcome.ac.uk/node30075.html

    40. BBC News | NEWSNIGHT | Genome Transcript - 12/2/01
    Transcript of a discussion with David Baltimore, John Sulston and David Bentley about the project.
    http://news.bbc.co.uk/1/hi/events/newsnight/1173801.stm
    low graphics version feedback help You are in: Events: Newsnight Front Page World ... AudioVideo
    This transcript has been typed at speed, and therefore may contain mistakes. Newsnight accepts no responsibility for these. However, we will be happy to correct serious errors. Who owns the map of the human body? SUSAN WATTS:
    Wherever we look, our world has been conquered. We've trodden its contours, mapped its every detail and understand what it holds. Today, a new exploration has begun - the exploration of ourselves. Scientists have had a rough map of our genes since last summer, but only now are they beginning to make sense of this new terrain. It's turning out to be an exhilarating journey. DAVID BALTIMORE:
    President, California Institute of Technology
    Shivers ran down my spine because I realised that we were seeing human beings opened to investigation with a depth we'd never seen before. JOHN SULSTON:
    International Human Genome Project
    This is an iconic moment when we say we've got to this point - it's only the beginning not the end, in fact it's only halfway through the beginning. WATTS:
    SULSTON:
    Without that, not only would we have a privatised genome, but we would not have a genome at all.

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