1. Pharmacology > Pharmacologists > Gilman, Alfred G. BIOGRAPHICAL MEMOIRS National Academy of Sciences Alfred Gilman February 5, 1908 January 13, 1984 By Murdoch Ritchie ALFRED GILMAN, an internationally renowned pharmacologist http://www.einet.net/directory/181917/Gilman_Alfred_G.htm

2. Biographies Of Alfred G. Gilman Biographies of Gilman Alfred G. and more Gilman Alfred G. biography. http://www.biography-center.com/biographies/1206-Gilman_Alfred_G_.html

Home Suggest a Biography Forum Contact ... Highest Rated Browse by Letter : A B C D ... Z Alfred G. Gilman -99999 ) Category ( ) suggest a correction Rating Rating Rate 0(broken link) www.nobel.se/medicine/laureates/1994/index.html Comment on this link Title : Medicine 1994 Rating Rating Rate 0(broken link) www.nobel.se/medicine/laureates/1994/gilman-autobi... Comment on this link Title : Alfred G. Gilman - Autobiography Suggest another Link for this biography Biographies beginning with Biographes by Category Most popular biographies ... Add details to this biogaphy Biography-Center.com is a directory of other biographies on the web. We allow comments on the links we supply, as well as an opportunity for you to rate these bio's. When you suggest a biography, you have the option of using our web based editor to enter a biography of your own. We receive numerous requests every day to add links Needless to say, most of the links have nothing to do with biographies and are generally discarded. If we miss your suggestion, please feel free to submit your biographies again for review. We also get a lot of requests for posting links on biography center. People are willing to pay a decent price for this however, we do not participate in this sort of activity. Please don’t ask.

3. Dictionary - MSN Encarta Enter a search term above to find Dictionary definitions or click the Thesaurus tab to find synonyms and antonyms. http://www.encarta.msn.com/encyclopedia_761582568/Gilman_Alfred_G_.html

4. Edgar Filing GILMAN ALFRED G - Form 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). http://finance.boston.com/boston/action/getedgarwindow?accesscode=12378991000002

5. Gilman - Definition And More From The Free Merriam-Webster Dictionary Definition of word from the MerriamWebster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word games. http://mw1.merriam-webster.com/dictionary/gilman

6. Gilman, Alfred G. Gilman, Alfred G., in full ALFRED GOODMAN GILMAN (b. July 1, 1941, New Haven, Conn., U.S.), American pharmacologist who shared the 1994 Nobel Prize in Physiology or Medicine http://www.uv.es/EBRIT/micro/micro_711_33.html

Britannica CD Index Articles Dictionary Help Gilman, Alfred G., in full ALFRED GOODMAN GILMAN (b. July 1, 1941, New Haven, Conn., U.S.), American pharmacologist who shared the 1994 Nobel Prize in Physiology or Medicine with American biochemist Martin Rodbell for their separate research in discovering cell-signaling transducers known as G -proteins. Gilman's father, Alfred, was a founding director of the pharmacology department at the Albert Einstein School of Medicine in New York City. Gilman was educated at Yale University (B.S., 1962) and at Case Western Reserve University (M.D. and Ph.D., 1969), where he studied under Nobel Prize recipient Earl W. Sutherland, Jr. Gilman worked at the National Institutes of Health (1969-71) and taught at the University of Virginia (1971-81) before becoming the director of the pharmacology department at the University of Texas Southwestern Medical Center in Dallas in 1981. Furthering Rodbell's hypotheses of the 1960s, Gilman showed, in the 1970s, that leukemic cells with mutant genes lack the G-protein that ensures proper cellular communication in normal cells. He successfully isolated, purified, and crystallized numerous G-proteins, which are so named because they bind to a nucleotide called guanosine triphosphate, or GTP. His experimentation led to a better understanding of many diseases, including cholera, whooping cough, and cancer. Related Propaedia Topics: Cell biology: cancer research, microbiology, radiation biology, tissue culture, transplantation biology

7. Re: Zydowscy Laurteaci Nobla (2-49) Medycyna 1994 Gilman, Alfred G. for their discovery of Gproteins and the role of these proteins in signal transduction in cells USA 1994 Rodbell, Martin http://newsgroups.derkeiler.com/Archive/Soc/soc.culture.polish/2007-09/msg00293.

Re: Zydowscy Laurteaci Nobla (2-49) Medycyna From herrman321@xxxxxxx Date : Sun, 02 Sep 2007 18:22:16 -0700 On Sep 2, 5:21 pm, "Alexander Sharon" <a.sha...@xxxxxxx> wrote: Year Nobel Laureate Country of birth 2006 Fire, Andrew Z. "for their discovery of RNA interference - gene silencing by double-stranded RNA" USA 2004 Axel, Richard "for their discoveries of odorant receptors and the organization of the olfactory system" USA 2002 Brenner, Sydney "for their discoveries concerning genetic regulation of organ development and programmed cell death" South Africa 2002 Horvitz, H. Robert "for their discoveries concerning genetic regulation of organ development and programmed cell death" USA 2000 Greengard, Paul "signal transduction in the nervous system" USA 2000 Kandel, Eric R. "signal transduction in the nervous system" Austria 1998 Furchgott, Robert F. "for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular system" USA

8. Summary For GILMAN ALFRED G - Www.implu.com GILMAN ALFRED G employment history and contact information available at www.implu.com http://www.implu.com/person/47141

9. Disulfiram - Dose, Causes, Effects, Therapy, Drug, Person, People, Used, Medicat Gilman, Alfred G. The Pharmacological Basis of Therapeutics. New York, NY McGrawHill, 1996. Kay, Jerald. PsychiatryBehavioral Science and Clinical http://www.minddisorders.com/Del-Fi/Disulfiram.html

Powered by JRank Encyclopedia of Mental Disorders Mental Disorders Del-Fi Disulfiram Definition Disulfiram is an aldehyde dehydrogenase inhibitor. It prohibits the activity of aldehyde dehydrogenase, an enzyme found in the liver. In the United States, disulfiram is sold under brand name Antabuse. Purpose Disulfiram is used as a conditioning treatment for alcohol dependence. When taken with alcohol, disulfiram causes many unwanted and unpleasant effects, and the fear of these is meant to condition the patient to avoid alcohol. Description Two Danish physicians who were investigating disulfiram for its potential benefits to destroy parasitic worms took disulfiram and became sick at a cocktail party. After a series of pharmacological and clinical studies, it was determined that disulfiram interacts with alcohol. Disulfiram by itself is not toxic. If taken with alcohol, however, it alters certain steps in the breakdown of alcohol. When alcohol is ingested, it is converted first to a chemical called acetaldehyde. Acetaldehyde is further broken down into acetate. In order for acetaldehyde to be broken down into acetate, aldehyde dehydrogenase needs to be active. Disulfiram is an aldehyde dehydrogenase inhibitor. Since disulfiram blocks the activity of aldehyde dehydrogenase, acetaldehyde cannot be broken down and the levels of acetaldehyde become five to ten times higher than the normal levels. This causes uncomfortable effects that encourage the person to avoid alcohol.

10. Alfred G. Gilman - Autobiography Nobelprize.org, The Official Web Site of the Nobel Prize http://nobelprize.org/nobel_prizes/medicine/laureates/1994/gilman-autobio.html

Home FAQ Press Contact Us ... Nobel Prize in Medicine Alfred G. Gilman - Autobiography About the Nobel Prizes Facts and Lists Nobel Prize in Physics Nobel Prize in Chemistry ... Nobel Prize Award Ceremonies Sort and list Nobel Prizes and Nobel Laureates Create a List All Nobel Prizes Nobel Prize Awarded Organizations Women Nobel Laureates Nobel Laureates and Universities Prize category: Physics Chemistry Medicine Literature Peace Economics The Nobel Prize in Physiology or Medicine 1994 Alfred G. Gilman, Martin Rodbell The Nobel Prize in Physiology or Medicine 1994 Summary Press Release Illustrated Information ... Other Resources Autobiography My father, Alfred Gilman, could play almost any musical instrument and frequently did so at neighborhood parties; his father owned a music store in Bridgeport, Connecticut. My mother, Mabel Schmidt Gilman, was an excellent pianist and gave lessons; her father was a professional trombonist, also in Bridgeport. Despite this heritage, my musical career ended after a few years of mediocre performance with the Yale University Concert Band during my days in college. There were more substantial influences. My father had turned to science, receiving his Ph.D. in Physiological Chemistry from Yale in 1931 for "Chemical and Physiological Investigations on Canine Gastric Secretion". He then joined the faculty of the Department of Pharmacology at the Yale Medical School, where he and Louis S. Goodman, a young M.D., became colleagues and close friends. A major new textbook of Pharmacology

11. Lorazepam - Dose, Children, Effects, Withdrawal, Drug, People, Used, Medication, Gilman, Alfred G. The Pharmacological Basis of Therapeutics. New York McGrawHill, 1996. Kaplan, Harold. Comprehensive Textbook of Psychiatry. ladelphia http://www.minddisorders.com/Kau-Nu/Lorazepam.html

Powered by JRank Encyclopedia of Mental Disorders Mental Disorders Kau-Nu Lorazepam Definition Lorazepam, a mild tranquilizer in the class of drugs known as benzodiazepines is a sold in the United States under brand names Alzapam, Ativan, or Loraz. It is also available generically. Purpose Lorazepam is used for management of anxiety, nausea and vomiting, insomnia , and seizures . Lorazepam is also used prior to surgery to produce sedation, sleepiness, drowsiness, relief of anxiety, and a decreased ability to recall the events surrounding the surgery. Description Lorazepam is a member of the benzodiazepine family. Benzodiazepines primarily work by enhancing the function of a certain naturally occurring brain chemical, gamma aminobutyric acid (GABA), that is responsible for inhibiting the transmission of nervous impulses in the brain and spinal cord. At the same time, the enhancement of GABA in the brain decreases symptoms associated with anxiety. Lorazepam differs from drugs such as diazepam (Valium) and chlordiazepoxide (Librium) in that it is shorter acting and does not accumulate in the body after repeated doses.

12. Insider Trading - Gilman Alfred G - Portfolio Holdings (Majority Ownership) Gilman Alfred G form 4 sec filings insider trading and stock options reveal insider stocks held, purchased, sold, portfolio holdings (majority ownership), and stock options http://www.secform4.com/insider-trading/1225473.htm

13. Alfred G. Gilman: Facts, Discussion Forum, And Encyclopedia Article The United States of America is a federal constitutional republic comprising fifty states and a federal district. The country is situated mostly in central North America, where http://www.absoluteastronomy.com/topics/Alfred_G._Gilman

Home Discussion Topics Dictionary ... Login Alfred G. Gilman Alfred G. Gilman Topic Home Discussion Discussion Ask a question about ' Alfred G. Gilman Start a new discussion about ' Alfred G. Gilman Answer questions from other users Full Discussion Forum Encyclopedia Alfred Goodman Gilman (born July 1, 1941) is an American United States The United States of America is a federal constitutional republic comprising fifty states and a federal district. The country is situated mostly in central North America, where its forty-eight contiguous states and Washington, D... pharmacologist Pharmacology Pharmacology is the study of drug action. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals... and biochemist Biochemistry Biochemistry is the study of the chemical processes in living organisms. It deals with the structures and functions of cellular components such as proteins, carbohydrates, lipids, nucleic acids and other biomolecules... . He shared the 1994 Nobel Prize in Physiology or Medicine Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine administered by the Nobel Foundation, is awarded once a year for outstanding contributions in the medical field. It is one of five Nobel Prizes established in 1895 by Swedish chemist Alfred Nobel, the inventor of dynamite, in his will, the others being...

14. Alfred G. Gilman Winner Of The 1994 Nobel Prize In Medicine Alfred G. Gilman, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. http://nobelprizes.com/nobel/medicine/1994a.html

A LFRED G G ILMAN 1994 Nobel Laureate in Medicine for discovery of G-proteins and the role of these proteins in signal transduction in cells. Background Born: 1941 Residence: U.S.A Affiliation: University of Texas Southwestern Medical Center, Dallas, TX Featured Internet Links Prize co-recipient Martin Rodbell Search WWW Search The Nobel Prize Internet Archive Nobel News Links Two from US share Nobel Prize in Medicine 'G Proteins' seen key to cell links Links added by Nobel Internet Archive visitors Something about cell regulation by Alfred Gilman (submitted by Bill King) UT Southwestern - Impact of Nobel Prizes Winner of The Gairdner Foundation Int'l Award Genbrain Biosystem Network (submitted by Bangzhe J. Zeng Information About Alfred G. Gilman (submitted by Kelly) Alfred Gilman Biography from Encyclopedia Britannica (submitted by www.britannica.com) Alfred Goodman Gilman (submitted by Lukas) B. J. Zeng, On the concept of system biological engineering (system biotechnology), Communication on Transgenic Animals, June 5, 1994 No. 6. (submitted by genbrain) Back to The Nobel Prize Internet Archive Literature Peace Chemistry ... Medicine We always welcome your feedback and comments

15. Abstracts: Invasion Of The Nucleotide Snatchers: Structural Insights Into The Me author Lee, Ethan, Gilman, Alfred G., Sprang, Stephen R., Coleman, David E., Wall, Mark A., IngiguezLluhi, Jorge A., Posner, Bruce A. http://www.faqs.org/abstracts/Biological-sciences/Invasion-of-the-nucleotide-sna

@import "/abstracts/css/default.css"; Abstracts search Faqs.org homepage Abstracts index Biological sciences Invasion of the nucleotide snatchers: Structural insights into the mechanism of G protein GEFs Article Abstract: Replacement of GDP by GTP in the active G protein site requires the help of a guanine nucleotide exchange factor (GEF). GEFs are structurally diverse, and the structures of two new complexes have recently been elucidated, Ras with the CDC25 domain of Sos1, and ARF1 with the Sec7 domain of the S. cerevisiae protein Gea2. The new structures, together with previously determined GDP and GTP bound complexes of G proteins, offer an insight into the mechanism of activation by nucleotide exchange factors. author: Sprang, Stephen R., Coleman, David E. Publisher: Elsevier B.V. Publication Name: Cell Subject: Biological sciences ISSN: Year: Observations, Nucleotides User Contributions: Comment about this article or add new information about this topic: Comment: (50-4000 characters) Name: E-mail: Security Code: Display my email: The structure of the G protein Heterotrimer G(sub i-alpha)-beta(sub 1)-gamma (sub 2) Article Abstract: The G protein heterotrimer formed by the alpha(sub i1), beta(sub 1) and gamma(sub 2) subunits is an asymmetrical molecule which is stabilized by interactions between the alpha and beta subunits. These interactions are necessary for the formation of the heterotrimer. The beta subunit forms a propeller domain containing seven motifs. There are two nonoverlapping contact sites between the alpha and beta subunits and an extended interface between beta and gamma.

16. Gilman, Alfred G. Gilman, Alfred G. (1941) My father, Alfred Gilman, could play almost any musical instrument and frequently did so at neighborhood parties; his father owned a http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/G/Gilman1/Gilman

Gilman, Alfred G. My father, Alfred Gilman, could play almost any musical instrument and frequently did so at neighborhood parties; his father owned a music store in Bridgeport, Connecticut. My mother, Mabel Schmidt Gilman, was an excellent pianist and gave lessons; her father was a professional trombonist, also in Bridgeport. Despite this heritage, my musical career ended after a few years of mediocre performance with the Yale University Concert Band during my days in college. There were more substantial influences. My father had turned to science, receiving his Ph.D. in Physiological Chemistry from Yale in 1931 for "Chemical and Physiological Investigations on Canine Gastric Secretion". He then joined the faculty of the Department of Pharmacology at the Yale Medical School, where he and Louis S. Goodman, a young M.D., became colleagues and close friends. A major new textbook of Pharmacology The Pharmacological Basis of Therapeutics, was the fruit of the Goodman and Gilman collaboration, first published in 1941. I too was born in 1941 (in New Haven, Connecticut) and named Alfred Goodman Gilman. Perhaps my fate was sealed from that day; as my friend Michael Brown once said, I am probably the only person who was ever named after a textboook. The bulk of my childhood was spent in a suburb of New York City, White Plains, while my father was first on the faculty of The College of Physicians and Surgeons of Columbia University and then the founding Chairman of Pharmacology at the new

17. Gillyflowers - Definition Of Gillyflowers By The Free Online Dictionary, Thesaur Gilly Gilly Gilly (Vaud) Gilly VD Gilly, Switzerland gillyflower gillyflower gillyflower gillyflower gillyflowers Gilman Gilman, Alfred Gilman, Alfred G. http://www.thefreedictionary.com/gillyflowers

18. Can Potassium Citrate Replace Sodium Bicarbonate And Potassium Chloride Of Oral Guerrant Richard L, Brunton Laurence L, Schnaitman Terry C, Rebhun Lionel I, Gilman Alfred G. Cyclic Adenosine Monophosphate and Alteration of Chinese Hamster Ovary Cell Morphology http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1777444/

window.name="mainwindow"; initRedirectClicks('/pmc/extredirect/') Journal List Arch Dis Child v.60(9); Sep 1985 Formats: Summary Page Browse PDF (534K) Arch Dis Child. 1985 September; PMCID: Can potassium citrate replace sodium bicarbonate and potassium chloride of oral rehydration solution? M R Islam This article has been cited by other articles in PMC. Abstract Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (534K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References Selected References These references are in PubMed. This may not be the complete list of references from this article. Hirschhorn N. Letter: Single solution for oral therapy of diarrhoea. Lancet. 1975 Nov 22; PubMed Garrow JS, Pike MC. The long-term prognosis of severe infantile malnutrition. Lancet. 1967 Jan 7; PubMed Molla AM, Rahman M, Sarker SA, Sack DA, Molla A. Stool electrolyte content and purging rates in diarrhea caused by rotavirus, enterotoxigenic E. coli, and V. cholerae in children. J Pediatr.

19. Paki.Ws Pakistani Music Articles Infos Alfred G. Gilman Pakistani Music Website. Alfred Goodman Gilman (born July 1, 1941) is an American pharmacologist and biochemist. http://music.paki.ws/Articles-Info_Result.php?title=Alfred_G._Gilman

20. Alfred G. Gilman (American Pharmacologist) -- Britannica Online Encyclopedia Alfred G. Gilman (American pharmacologist), July 1, 1941New Haven, Conn., U.S.American pharmacologist who shared the 1994 Nobel Prize for Physiology or Medicine with American http://www.britannica.com/EBchecked/topic/233809/Alfred-G-Gilman

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