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         Guillemin Roger:     more books (16)
  1. The Nobel Duel by Nicholas Wade, 1981-09
  2. UNITY AND VARIETY IN MUSLIM CIVILIZATION, WITH PAPERS BY ARMAND ABEL; J.N.D. ANDERSON; ROBERT BRUNSCHVIG; CLAUDE CAHEN; WERNER CASKEL; G.W.J. DREWES; JACQUES DUCHESNE-GUILLEMIN; RICHARD ETTINGHAUSEN; FRANCESCO GABRIELI; G.E. VON GRUNEBAUM; ROGER LE TOURNEAU; BERNARD LEWIS; FRITZ MEIER; VLADIMIR MINORSKY; JOSEPH SCHACHT; BERTOLD SPULER. by Gustave E. von, ed. Grunebaum,

21. Guillemin, Roger --  Kids Encyclopedia | Online Encyclopedia | Kids Online Dicti
Guillemin, Roger (born 1924), U.S. physiologist, born in Dijon, France; to U.S. 1953, naturalized 1965; professor Baylor College of Medicine, Houston, 195370; at Salk
http://kids.britannica.com/comptons/article-9325413/Guillemin-Roger

22. Roger Charles Louis Guillemin — FactMonster.com
Encyclopedia Guillemin, Roger Charles Louis. Guillemin, Roger Charles Louis (gēy u măN') , 1924–, FrenchAmerican physiologist, b. Dijon, France.
http://www.factmonster.com/ce6/people/A0822102.html

23. Roger Guillemin Winner Of The 1977 Nobel Prize In Medicine
Roger Guillemin, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive.
http://almaz.com/nobel/medicine/1977a.html
R OGER G UILLEMIN
1977 Nobel Laureate in Medicine
    for their discoveries concerning the peptide hormone production of the brain
Background
    Born: 1924
    Place of Birth: Dijon, France
    Residence: U.S.A.
    Affiliation: The Salk Institute, San Diego, CA
Featured Internet Links Links added by Nobel Internet Archive visitors Back to The Nobel Prize Internet Archive
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Peace Chemistry ... Medicine We always welcome your feedback and comments

24. The Age Of The Clans: The Highlands From Somerled To The Clearances
Guillemin, Roger Charles Louis Encyclopedia article; The Columbia Encyclopedia, Sixth Edition, 2009. Read Guillemin, Roger Charles Louis at Questia library.
http://www.questia.com/PM.qst?a=o&d=117021787

25. Facts About Guillemin, Roger, As Discussed In Britannica Compton's Encyclopedia
Facts about Guillemin, Roger, (born 1924), U.S. physiologist, born in Dijon, France; to U.S. 1953, naturalized 1965; professor Baylor College of Medicine, Houston, 1953–70
http://www.britannica.com/facts/11/916196/Guillemin-Roger-as-discussed-in-Guille
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    Facts about Guillemin, Roger, as discussed in Britannica Compton's Encyclopedia Guillemin, Roger
    (born 1924), U.S. physiologist, born in Dijon, France; to U.S. 1953, naturalized 1965; professor Baylor College of Medicine, Houston, 1953–70; at Salk Institute and University of California, San Diego, 1970–; received 1977 Nobel prize for research on hormone production in the brain. see also in index Nobel Prizewinners, Get Random Facts Britannica Content: Other Britannica sites:
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26. AccessScience | Biography | Guillemin, Roger Charles Louis
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http://www.accessscience.com/content.aspx?id=M0090454

27. McGraw-Hill's AccessScience
About AccessScience. AccessScience is a subscriptionbased website that features continually updated scientific and
http://www.accessscience.com/content.aspx?searchStr=Radioimmunoassay&id=M009

28. Roger Charles Louis Guillemin — Infoplease.com
More on Roger Charles Louis Guillemin from Infoplease Guillemin meaning and definitions Guillemin Definition and Pronunciation; See more Encyclopedia articles on
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29. Guillemin, Roger Charles Louis Synonyms, Guillemin, Roger Charles Louis Antonyms
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30. Guillemin, Roger Charles Louis
Guillemin, Roger Charles Louis (b. Jan. 11, 1924, Dijon, Fr.), Frenchborn American physiologist whose researches into the hormones produced by the hypothalamus gland resulted in
http://www.uv.es/EBRIT/micro/micro_250_65.html
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Guillemin, Roger Charles Louis
(b. Jan. 11, 1924, Dijon, Fr.), French-born American physiologist whose researches into the hormones produced by the hypothalamus gland resulted in his being awarded a share (along with Andrew Schally and Rosalyn Yalow) of the Nobel Prize for Physiology or Medicine in 1977. Among Guillemin's achievements were the isolation of the first hypothalamic hormone to be discovered, TRH ( thyrotropin -releasing hormone); the isolation and synthesis of somatostatin , a hypothalamic hormone that regulates activities of the pituitary gland and the pancreas; and the discovery of a new class of hormonal substances called endorphins. Related Propaedia Topics: The Structures and Functions of Organisms

31. Guillemin, Roger C(harles) L(ouis) - Encyclopedia Britannica - On History
Full Name Roger C. L. Guillemin. Nationality American Activity American physiologist. Born 1101-1924
http://www.history.co.uk/encyclopedia/guillemin-roger-c-harles-l-ouis-.html

32. Roger Charles Louis Guillemin
Nobel Winners picture, Nobel Winners Bio Roger Charles Louis Guillemin (1924) Frenchborn American physiologist whose researches into the hormones produced by the
http://www.nobel-winners.com/Medicine/roger_charles_louis_guillemin.html
Roger Charles Louis Guillemin
Roger Charles Louis Guillemin
French-born American physiologist whose researches into the hormones produced by the hypothalamus gland resulted in his being awarded a share (along with Andrew Schally and Rosalyn Yalow) of the Nobel Prize for Physiology or Medicine in 1977.
Guillemin was educated at the universities of Dijon, Lyon, and Montreal. He taught at the Baylor College of Medicine in Houston, Texas, from 1953 to 1970, except for the years 1960-63, when he was on the faculty of the College de France in Paris. From 1970 he was a resident fellow and research professor at the Salk Institute for Biological Studies in La Jolla, Calif. Guillemin became a U.S. citizen in 1963. Guillemin proved the hypothesis that the hypothalamus releases hormones that regulate the pituitary gland. Among the hypothalamic hormones that he and his colleagues discovered, isolated, analyzed, or synthesized were TRH (thyrotropin-releasing hormone), which regulates thyroid activity; GHRH (growth hormone-releasing hormone), which causes the pituitary to release gonadotropin; and somatostatin, which regulates the activities of the pituitary gland and the pancreas. Guillemin also discovered an important class of proteins called endorphins that are involved in the perception of pain.

33. Roger Guillemin: Biography From Answers.com
(born Jan. 11, 1924, Dijon, Fr.) Frenchborn U.S. physiologist. He and his colleagues discovered, isolated, and synthesized hypothalamic hormones that regulate thyroid
http://www.answers.com/topic/guillemin-roger-charles-louis

34. Guillemin, Roger Charles Louis
Frenchborn US endocrinologist. He has isolated and identified various hormones, for which he received the 1977 Nobel Prize for Physiology or Medicine, together
http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/G/Guillemin/1.ht
Guillemin, Roger Charles Louis
French-born US endocrinologist. He has isolated and identified various hormones, for which he received the 1977 Nobel Prize for Physiology or Medicine, together with his co-worker Andrew Schally (1926- ) and US physicist Rosalyn Yalow . Guillemin also discovered endorphins.
Guillemin was born in Dijon and educated there and at Lyon. He moved to the USA 1953 and did most of his work at Baylor College of Medicine, Houston, Texas, becoming professor 1963. In 1970 he joined the Salk Institute in La Jolla, California.
Guillemin found that the brain controls the pituitary gland by means of hormones produced by central neurons - the neurosecretory cells of the hypothalamus. He worked with Lithuanian refugee Schally 1957-62, and later their investigations were parallel. Between 1968 and 1973 they isolated and synthesized three hypothalamic hormones which regulate the secretion of the anterior pituitary gland.

35. Roger Charles Louis Guillemin (American Physiologist) -- Britannica Online Encyc
Facts about Guillemin, Roger, as discussed in Britannica Compton's Encyclopedia Guillemin, Roger When was Roger Charles Louis Guillemin born? Where was Roger Charles Louis Guillemin
http://www.britannica.com/EBchecked/topic/248741/Roger-Charles-Louis-Guillemin
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Roger Charles Louis Guillemin
Table of Contents: Roger Charles Louis Guillemin Article Article Additional Reading Additional Reading Supplemental Information Supplemental Information - Spotlights Spotlights External Web sites External Web sites Citations

36. Roger | Define Roger At Dictionary.com
–interjection 1. Informal . all right; O.K. 2. message received and understood (a response to radio communications). 3. ( often initial capital letter ) Jolly Roger. 4
http://dictionary.reference.com/browse/roger

37. Ten Nobels For The Future
Guillemin, Roger C.L. Medicine, 1977 Hoffmann, Roald Chemistry, 1981 Jacob, Fran ois Medicine, 1965 Kindermans, JeanMarie Peace 1999
http://www.hypothesis.it/nobel/eng/bio/guillemin.htm

Allais, Maurice
Economics, 1988
Altman, Sidney
Chemistry, 1989
Arber, Werner
Medicine, 1978
Arrow, Kenneth J.
Economics, 1972
Baltimore, David
Medicine, 1975
Becker, Gary S.
Economics, 1992
Black, James W.
Medicine, 1988
Brown, Lester R.

Buchanan, James M.
Economics, 1986
Charpak, Georges
Physics, 1992 Dahrendorf, Ralf Dausset, Jean Medicine, 1980 Economics, 1983 de Duve, Christian Medicine, 1974 Dulbecco, Renato Medicine, 1975 Ernst, Richard R. Chemistry, 1991 Esaki, Leo Physics, 1973 Fo, Dario Literature, 1997 Gell-Mann, Murray Physics, 1969 Glashow, Sheldon Lee Physics, 1979 Guillemin, Roger C.L. Medicine, 1977 Hoffmann, Roald Chemistry, 1981 Jacob, François Medicine, 1965 Kindermans, Jean-Marie Peace 1999 Klein, Lawrence R. Economics, 1980 Kroto, Harold W. Chemistry, 1996 Lederman, Leon M.

38. Gonadostatin
Ling, Nicholas C.; Guillemin, Roger C. L.; Ying, ShaoYao; Esch, Frederick S.; A substantially purified substance has been isolated from bovine gonadal
http://www.devileye.net/catalog/dental_x-ray_duplicator/gonadostatin.html
Gonadostatin
Ling, Nicholas C.; Guillemin, Roger C. L.; Ying, Shao-Yao; Esch, Frederick S.; A substantially purified substance has been isolated from bovine gonadal secretions which mediates pituitary hormone secretion, using an extraction and purification sequence that includes gel filtration, partition chromatography and HPLC in that order. The substance, designated gonadostatin, is a moderate-size peptide which below a threshold level selectively inhibits LRF-stimulated pituitary secretion of LH and FSH. Above a threshold level, gonadostatin generally stimulates pituitary hormone secretion. The present invention relates to peptides which influence the release of hormones by the anterior pituitary gland.
BACKGROUND OF THE INVENTION
SUMMARY OF THE INVENTION
A substantially pure substance, which is primarily protein in nature, has been isolated from mammalian seminal plasma. The substance, designated gonadostatin, selectively inhibits LRF-induced secretions of FSH and LH and has a molecular weight of about 11,000, as measured by gel filtration. The purification of gonadostatin is achieved by gel filtration, followed by partition chromatography, followed by reverse-phase high performance liquid chromatography (HPLC), with selection of fractions exhibiting gonadostatin activity at each step.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
In accordance with the present invention, a substance, designated gonadostatin, has been isolated from bovine seminal plasma (BSP) which according to HPLC and N-terminal analysis criteria shows a purity greater than 99% by weight. When added to an in vitro culture of rat anterior pituitary cells, gonadostatin, in concentrations of up to about 50 .mu.g/ml., inhibits LRF-induced pituitary secretion of LH and FSH. Higher doses of gonadostatin generally promote the secretion of pituitary hormones including LH, FSH and TSH.

39. ROGER GUILLEMIN - Encyclopédie Universalis
–noun 1. Bernard, 1893–1968, U.S. composer. 2. Bruce, 1870–1957, U.S. book designer and printer. 3. Carl (Ransom), 1902–87, U.S. psychologist. 4. Ginger ( Virginia
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GUILLEMIN ROGER
Physiologiste américain d'origine française, Prix Nobel de physiologie ou médecine en 1977 (conjointement à Andrew Schally et Rosalyn Yalow) pour ses recherches sur les hormones hypothalamiques. Roger Charles Louis Guillemin est né le 11 janvier 1924 à Dijon. Il fait ses études à l'université de Dijon, puis à celles de Lyon et de Montréal. Il devient enseignant à l'école de médecine Baylor, à Houston (Texas), de 1953 à 1970, avec une interruption de 1960 à 1963, pendant laquelle il enseigne au Collège de France, à Paris. À partir de 1970, il devient membre résident, puis professeur-chercheur à l'Institut Salk pour la recherche biologique, à La Jolla, en Californie. Il a pris la nationalité américaine en 1963. Roger Guillemin a confirmé l'hypothèse selon laquelle l'hypothalamus sécrète des […] … pour nos abonnés, l'article se prolonge sur 1 page…
Thématique
Classification thématique de cet article :

40. DNA Encoding Follistatin
Ling, Nicholas C. K.; Ueno, Naoto; Shimasaki, Shunichi; Esch, Frederick S.; Ying, ShaoYao; Guillemin, Roger C. L.;
http://www.devileye.net/catalog/clamping_terminal_unit/dna_encoding_follistatin.
DNA encoding follistatin
Ling, Nicholas C. K.; Ueno, Naoto; Shimasaki, Shunichi; Esch, Frederick S.; Ying, Shao-Yao; Guillemin, Roger C. L.; The present invention relates to a protein having inhibin-like activity isolated substantially to homogeneity from bodily material obtained from porcine animals and which is referred to as follistatin.
BACKGROUND OF THE INVENTION
SUMMARY OF THE INVENTION
In accordance with the present invention, two proteins, one having a molecular weight of about 35,000 daltons (35K) and the other about 32,000 daltons (32K) and both having inhibin activity have been successfully isolated from porcine follicular fluid. These two proteins have been completely characterized using microsequencing and molecular biological methods. Using the porcine amino acid sequence information, cDNA clones encoding these proteins were identified from a porcine ovarian cDNA library. Then, using the porcine cDNA as a probe, the cloning and sequencing of the corresponding human and rat proteins were accomplished.
More specifically, the proteins were first isolated and purified to substantial homogeneity from material obtained from the bodies of porcine animals and are hereinafter referred to as Follistatin A and Follistatin B. Each protein is composed of a single polypeptide chain. Microsequencing showed that the amino-terminal amino acid residue sequence of both proteins was Gly-Asn-Cys-Trp-Leu-Arg-Gln-Ala-Lys-Asn-Gly-Arg-Cys-Gln-Val-Leu. It was also ascertained that the next eight residues of Follistatin A were Tyr-Lys-Thr-Glu-Leu-Ser-Lys-Glu. Follistatin A has now been completely characterized as a result of further microsequencing and the use of molecular biological techniques. Each protein exhibits inhibin-like activity in that it specifically inhibits basal secretion of FSH but does not inhibit basal secretion of luteinizing hormone (LH).

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