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  1. Robert Bruce Merrifield

21. Merrifield, Robert Bruce
Merrifield, Robert Bruce (1921) Bruce Merrifield was born in Fort Worth, Texas, July 15, 1921, the only son of George E. and Lorene (Lucas) Merrifield.
http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/M/merrifield/Mer
Merrifield, Robert Bruce Bruce Merrifield was born in Fort Worth, Texas, July 15, 1921, the only son of George E. and Lorene (Lucas) Merrifield. In the spring of 1923 they drove across the southwest desert to settle in California where they lived in several cities throughout the state. He attended nine grade schools and two high schools before graduating from Montebello High School in 1939. His interest in chemistry began there and he also enjoyed the astronomy club where he ground a mirror and built a small reflecting telescope. From Les Prix Nobel 1984.

22. The Nobel Prize In Chemistry 1984
Nobelprize.org, The Official Web Site of the Nobel Prize
http://nobelprize.org/nobel_prizes/chemistry/laureates/1984/
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The Nobel Prize in Chemistry 1984
Bruce Merrifield
The Nobel Prize in Chemistry 1984
Robert Bruce Merrifield
The Nobel Prize in Chemistry 1984 was awarded to Bruce Merrifield "for his development of methodology for chemical synthesis on a solid matrix" TO CITE THIS PAGE:
MLA style: "The Nobel Prize in Chemistry 1984". Nobelprize.org. 1 Nov 2010 http://nobelprize.org/nobel_prizes/chemistry/laureates/1984/ Home FAQ ... Contact Us

23. APPARATUS FOR THE AUTOMATED SYNTHESIS OF PEPTIDES - Patent 3531258
Merrifield, Robert Bruce Stewart, John M. Jernberg, Nils
http://www.freepatentsonline.com/3531258.html

24. Merrifield, Robert Bruce - Personenlexikon
Robert Bruce Merrifield Merrifield, Robert Bruce Merrifield, Robert Bruce, 1921–2006, American chemist, b. Fort Robert Bruce Fraser PEIRCE - PEIRCE, Robert Bruce Fraser (1843
http://www.personenlexikon.net/d/merrifield-robert-bruce/merrifield-robert-bruce
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Merrifield, Robert Bruce
amerikanischer Biochemiker, geboren 15.7.1921 Fort Worth (Tex.); ab 1949 Mitarbeiter des biochemischen Labors des Rockefeller Institute for Medical Research in New York, seit 1966 Professor in New York; entwickelte 1962 ein Verfahren zur chemischen Synthese von Peptiden und Proteinen, bei dem die wachsenden Ketten während der Synthese an eine feste Matrix (z.B. Polystyrol) gebunden sind (Festphasensynthese); baute auf der Basis dieses Verfahrens 1965 mit seinen Mitarbeitern den Prototyp eines Syntheseautomaten, mit dem die (oft Monate betragende) Synthesedauer auf 1/50 der sonst benötigten Zeit verkürzt werden konnte; das auch als Merrifield-Synthese bezeichnete Verfahren, das 1969 erstmals zur Totalsynthese eines enzymatisch aktiven Proteins (Ribonuclease, bestehend aus 124 Aminosäuren) führte, konnte später auch auf die chemische Synthese von Polynucleotiden ausgedehnt werden; erhielt 1984 den Nobelpreis für Chemie. Diese Seite als Bookmark speichern : addthis_url = location.href; addthis_title = document.title; addthis_pub = 'woorgle1492';

25. Merrifield, Robert Bruce
Robert Bruce Merrifield (July 15, 1921 – May 14, 2006) was an American biochemist who won the Nobel Prize in Chemistry in 1984 for the invention of solid phase peptide synthesis.1
http://www.cartage.org.lb/fr/themes/Biographies/mainbiographie/M/Merrifield/Merr
Merrifield, Robert Bruce
En 1959 débute l'aventure qui le mènera au prix Nobel de chimie. Il y a eu, avant Merrifield, nous l'avons vu, d'autres lauréats du prix Nobel à avoir travaillé sur la synthèse des peptides, le premier d'entre eux ayant été Emil Fischer. Mais la date marquante reste l'année 1953 où a été réussie, par Vincent du Vigneaud la synthèse de l'oxytocine. La synthèse d'un peptide nécessite plusieurs étapes successives durant lesquelles s'enchaînent les différents acides animés. Opérer en milieu liquide, comme l'avait fait du Vigneaud, soulève d'énormes difficultés, car il faut à chaque étape isoler et purifier les intermédiaires de la réaction. Merrifield chercha donc à simplifier la méthode de synthèse; c'est en 1963 qu'il publie ses expériences, dévoilant la nouvelle méthode de synthèse des peptides sur support solide.
Cette méthode va rapidement dépasser le cadre de la synthèse peptidique, et avoir une portée générale en chimie organique, tout particulièrement dans la synthèse des polymères. Le grand mérite de Merrifield et de ses collaborateurs a été de réaliser un appareil automatique, programmé, qui peut avec des rendements élevés produire de façon répétitive les différentes étapes chimiques permettant l'addition de chaque aminoacide à une chaîne polypeptidique qui croît progressivement. Une séquence programmée de réactions s'effectue dans un seul réacteur, à l'aide de pompes calibrées, avec des réactifs ajoutés automatiquement à partir d'un réservoir: l'appareil tient compte des temps de réaction de chaque étape et, grâce à la "technique en phase solide", sépare les produits de la réaction des substances parasites.

26. ROBERT BRUCE MERRIFIELD - Encyclopédie Universalis
Robert Bruce Merrifield Merrifield, Robert Bruce Merrifield, Robert Bruce, 1921–2006, American chemist, b. Fort See more Encyclopedia articles on British and Irish History
http://www.universalis.fr/encyclopedie/robert-bruce-merrifield/
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MERRIFIELD ROBERT BRUCE
Les grands scientifiques inventent ou découvrent. Le chimiste américain Robert Bruce Merrifield, né à Fort Worth (Texas) le 15 juillet 1921, fut un inventeur. Ses études universitaires se déroulèrent à l'université de Californie, à Los Angeles, où il obtint son Ph.D. en 1949. Puis il reçut immédiatement un engagement dans le laboratoire du Dr. D. W. Woolley à l'Institut Rockefeller de recherches médicales, à New York, qui deviendra l'université Rockefeller. Nommé professeur titulaire en 1966, bénéficiaire d'une chaire John D. Rockefeller, Jr., en 1983, Merrifield y effectuera l'intégralité de sa carrière. Il eut d'abord à synthétiser des polypeptides, constitués de vingt à quarante acides aminés. Cela lui prenait un temps démesuré, plusieurs mois déjà pour les pentapeptides.  […] … pour nos abonnés, l'article se prolonge sur 1 page…
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27. Bruce Merrifield Biography, Pictures, Videos, Relationships - FamousWhy
Bruce Merrifield (Robert Bruce Merrifield) was born on Friday, July 15, 1921 in Fort Worth and he was a famous chemist from United States
http://people.famouswhy.com/bruce_merrifield/

28. It Happened In 1984
MERRIFIELD, ROBERT BRUCE, U.S.A., Rockefeller University, New York, NY, b.1921 for his development of methodology for chemical synthesis on a solid matrix
http://www.orgsites.com/ma/bhs1984/_pgg4.php3

29. 20th Century Year By Year 1984
MERRIFIELD, ROBERT BRUCE, U.S.A., Rockefeller University, New York, NY, b.1921 for his development of methodology for chemical synthesis on a solid
http://www.historycentral.com/20th/1984.html

30. Merrifield Robert Bruce -
A university is an institution of higher education and research, which grants academic degrees in a variety of subjects. A university is a corporation that provides both
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31. Robert Bruce Merrifield: Facts, Discussion Forum, And Encyclopedia Article
The United States of America is a federal constitutional republic comprising fifty states and a federal district. The country is situated mostly in central North America, where
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Discussion Ask a question about ' Robert Bruce Merrifield Start a new discussion about ' Robert Bruce Merrifield Answer questions from other users Full Discussion Forum Encyclopedia Robert Bruce Merrifield (July 15, 1921 – May 14, 2006) was an American United States The United States of America is a federal constitutional republic comprising fifty states and a federal district. The country is situated mostly in central North America, where its forty-eight contiguous states and Washington, D...
biochemist
Biochemist Biochemists are scientists who are trained in biochemistry. Typical biochemists study chemical processes and chemical transformations in living organisms. The prefix of "bio" in "biochemist" can be understood as a fusion of "biological chemist."-Role:...
who won the Nobel Prize in Chemistry Nobel Prize in Chemistry The Nobel Prize in Chemistry is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outstanding contributions in chemistry, physics, literature,...
in 1984 for the invention of solid phase peptide synthesis.

32. Merridew, Jack Definition Of Merridew, Jack In The Free Online Encyclopedia.
Merrifield's knife Merrifield's knife Merrifield, AlphaMethoxyphenyl Merrifield, R Bruce Merrifield, R. Bruce Merrifield, Robert Bruce merrihueite
http://encyclopedia2.thefreedictionary.com/Merridew, Jack

33. Science Fair Projects - Robert Bruce Merrifield
The Ultimate Science Fair Projects Encyclopedia Robert Bruce Merrifield
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Robert Bruce Merrifield
Robert Bruce Merrifield is an American biochemist He was born in Fort Worth Texas 15 July , the only son of George E. Merrifield and Lorene née Lucas. In the family moved to California where he attended nine grade schools and two high schools before graduating from Montebello High School in . It was there that he developed an interest both in chemistry and in astronomy After two years at Pasadena Junior College he transferred to the University of California at Los Angeles (UCLA). After graduation in chemistry he worked for a year at the Philip R. Park Research Foundation taking care of an animal colony and assisting with growth experiments on synthetic amino acid diets. One of these was the experiment by Geiger that first demonstrated that the essential amino acids must be present simultaneously for growth to occur.

34. FisicaNet - Biografía De Merrifield, Robert Bruce
Merrifield, Robert Bruce Robert Bruce Merrifield Jerne, Niels Kaj Niels Kaj Jerne; K hler, Georges J. F. Georges J. F. K hler; Milstein, C sar C sar Milstein
http://www.fisicanet.com.ar/biografias/nobelquimica/bibliografias3/merrifield.ph

35. Knowles William
Merrifield Robert Bruce. design by H5 . TheBestEdu. The text is property of free encyclopedia Wikipedia. For more information please click here.
http://www.thebestedu.com/bookmarks/chem/knowles-william.htm
William S. Knowles B iography - Nobel Prize Winner (2001)
William S. Knowles (born June 1, 1917) is an American chemist. He was born in Taunton, Massachusetts.
He shared one half of the Nobel Prize in Chemistry in 2001 with the Japanese chemist Ryoji Noyori for their work on enantioselective catalysed hydrogenation reactions.
He currently resides in St. Louis, Missouri.
LIST OF NOBEL PRIZE WINNERS IN CHEMISTRY PART II. Grignard Victor Grubbs Robert H Haber Fritz Hahn Otto ... Merrifield Robert Bruce design by H5
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36. CHEMISTS OF THE WORLD
Merrifield Robert Bruce Miller Stanley Moissan Henri Moore Peter Natta Giulio Nobel Alfred Onovalov Nikolai Vasilievitch Onsager Lars Ostwald Wilhelm
http://che-mix.utm.com.pl/biographies.html

37. Merrill - Definition Of Merrill By The Free Online Dictionary, Thesaurus And Enc
Merrifield, AlphaMethoxyphenyl Merrifield, R Bruce Merrifield, R. Bruce Merrifield, Robert Bruce merrihueite Merrilies, Meg Merrill Merrill Father Plowing Towing
http://www.thefreedictionary.com/Merrill

38. Merrier Legal Definition Of Merrier. Merrier Synonyms By The Free Online Law Dic
Merrifield's knife Merrifield's knife Merrifield, AlphaMethoxyphenyl Merrifield, R Bruce Merrifield, R. Bruce Merrifield, Robert Bruce merrihueite
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39. Robert Bruce Merrifield - Bio Of Robert Bruce Merrifield
Robert Bruce Merrifield was an American chemist and Nobel laureate.
http://chemistry.about.com/od/famouschemists/p/robertbrucemerrifieldbio.htm
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    Robert Bruce Merrifield:
    Robert Bruce Merrifield was an American chemist and Nobel laureate.
    Birth:
    July 15 , 1921 in Fort Worth, Texas
    Death:
    May 14 , 2006 in Cresskill, New Jersey
    Claim to Fame:
    Merrifield was an American biochemist who invented the process of solid phase peptide synthesis. Peptides would be built one amino acid at a time on a substrate of polymer to form custom chains and then the substrate would be chemically removed. This technique would earn him the 1984 Nobel Prize in Chemistry. Related Articles Guide since 2001 Anne Marie Helmenstine, Ph.D.

    40. Merrifield Family Crest
    View the Merrifield family crest and history. Discover the Merrifield family history for the Merrifield Origin. What is the origin of the name Merrifield.
    http://www.houseofnames.com/merrifield-family-crest
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    Merrifield Family Crest and Name History
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    Origin Displayed: English
    Where did the English Merrifield family come from? What is the English coat of arms/family crest? When did the Merrifield family first arrive in the United States? Where did the various branches of the family go? What is the history of the family name?
    The proud Merrifield family originated in Cornwall , a rugged coastal region in southwestern England . In early times, people were known by only a single name. However, as the population grew and people travelled further afield, it became increasingly necessary to assume an additional name to differentiate between bearers of the same personal name. The manner in which hereditary surnames arose is interesting.

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