1. Dictionary - MSN Encarta Enter a search term above to find Dictionary definitions or click the Thesaurus tab to find synonyms and antonyms. http://www.encarta.msn.com/encyclopedia_761582680/Sharp_Phillip_A_.html

2. Biographies Of Phillip A. Sharp Biographies of Sharp Phillip A. and more Sharp Phillip A. biography. http://www.biography-center.com/biographies/3002-Sharp_Phillip_A_.html

Home Suggest a Biography Forum Contact ... Highest Rated Browse by Letter : A B C D ... Z Phillip A. Sharp -99999 ) Category ( ) suggest a correction Rating Rating Rate 0(broken link) http://nobelprize.org/nobel_prizes/medicine/laurea... Comment on this link Title : Medicine 1993 Suggest another Link for this biography Biographies beginning with Biographes by Category Most popular biographies ... Add details to this biogaphy Biography-Center.com is a directory of other biographies on the web. We allow comments on the links we supply, as well as an opportunity for you to rate these bio's. When you suggest a biography, you have the option of using our web based editor to enter a biography of your own. We receive numerous requests every day to add links Needless to say, most of the links have nothing to do with biographies and are generally discarded. If we miss your suggestion, please feel free to submit your biographies again for review. We also get a lot of requests for posting links on biography center. People are willing to pay a decent price for this however, we do not participate in this sort of activity. Please don’t ask.

3. Phillip Sharp—biologist http//encarta.msn.com/encyclopedia_761582680/sharp_phillip_a_.html. Education Phillip A. Sharp, who was awarded the 2002 Biotechnology Heritage Award along with his colleague http://kyluka.com/briefing/Phillip_Sharp_biologist

Find your favorite... Related briefings Karl Ernst von Baer Linda Buck Edward Wilson Have a comment? Print Birth Phillip A. Sharp (born 1944) http://babynamer.com/category/491 Phillip Allen Sharp (born June 6 , 1944 ), U.S. geneticist and molecular biologist ; co-discovered gene splicing; shared the 1993 Nobel Prize in Physiology or Medicine with Richard ... http://encarta.msn.com/encyclopedia_761582680/Sharp_Phillip_A_.html Education http://www.chemheritage.org/exhibits/biotech/sharp.html Fame Richard J. Roberts and Phillip A. Sharp (1993 Nobel Prize) made their amazing discovery of the existence of split genes in the adenovirus, when they examined a hybridized nucleic acid molecule made between a adenoviral mRNA and its template DNA in the electron microscope. http://fig.cox.miami.edu/~cmallery/150/gene/split_genes.htm Rich Roberts and Phillip Sharp, 1993, Nobel Prize in Medicine and Physiology for their work on split genes and RNA processing or RNA splicing. http://en.wikibooks.org/wiki/Molecular_Biology/Milestones Work Phillip Sharp, Ph.D., of MIT and a founder of Biogen, receives the Nobel Prize in Medicine for his discovery of split genes

4. Sharp, Phillip A. Sharp, Phillip A., in full PHILLIP ALLEN SHARP (b. June 6, 1944, Falmouth, Ky., U.S.), American molecular biologist, awarded the 1993 Nobel Prize for Physiology or Medicine http://www.uv.es/EBRIT/micro/micro_541_28.html

Britannica CD Index Articles Dictionary Help Sharp, Phillip A., in full PHILLIP ALLEN SHARP (b. June 6, 1944, Falmouth, Ky., U.S.), American molecular biologist, awarded the 1993 Nobel Prize for Physiology or Medicine, along with Richard J. Roberts , for his independent discovery of "split genes." Sharp received a doctorate in chemistry from the University of Illinois at Urbana-Champaign in 1969. In that year he began working at the California Institute of Technology, moving to the Cold Spring Harbor Laboratory in New York in 1971. In 1974 he went to the Massachusetts Institute of Technology, where he did his prize-winning research. In 1977 Sharp helped found Biogen Ltd., a biotechnology company. In 1977 Sharp, working with a team that included Susan Berget and Claire Moore, discovered that a single molecule of messenger RNA (mRNA) from an adenovirus corresponded to four separate, discontinuous segments of DNA : the segments of DNA that code for proteins, now called exons , are separated by long stretches of DNA, now called introns , that do not contain genetic information. At the same time, a team working independently under Roberts came up with the same finding. Previously biologists had believed that genes were continuous stretches of DNA that served as direct templates for mRNA in the assembly of proteins; this model was based on studies of prokaryotic organisms such as bacteria. Following the discovery of Sharp and Roberts, it was demonstrated that the discontinuous gene structure is the most common one found in eukaryotes.

5. NIH VideoCasting Event Summary Sharp, Phillip A. National Institutes of Health (U.S.) Publisher Bethesda, Md. National Institutes of Health, 2007 Other Title(s) Biology and biochemistry of small RNA http://videocast.nih.gov/Summary.asp?File=14088

6. Sharp, Phillip A. Sharp, Phillip A. (1944) A sense of place was and remains an important part of my life. I was born in a rural community in the northern hill country of http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/S/Sharp/Sharp.ht

Sharp, Phillip A. A sense of place was and remains an important part of my life. I was born in a rural community in the northern hill country of Kentucky. My earliest memories are those of a child playing around the house on our family farm, located in a bend of the Licking River near McKinneysburg. My mother, Kathrin Colvin Sharp, had grown up in that same house and her family had been part of this community for many generations. My father, Joseph Walter Sharp, grew up nearby within walking distance of the nearest town and county-seat, Falmouth. Both parents came from large families and I was surrounded by grandparents, aunts, uncles, siblings and cousins. My formal education was entirely in the public schools of Pendleton County: McKinneysburg Elementary, Butler Elementary and High School and Pendleton County High School. Even though my studies never interfered with sports or fun, I managed to gain an appreciation of math and science. At the end of my stay at Caltech, I opted to extend my postdoctoral period and begin to study the structure and pathway of expression of genes in human cells. The expression of genes of animal viruses with DNA genomes was the only experimentally approachable system at that time, and this led me to a further postdoctoral year at Cold Spring Harbor Laboratory under the mentorship of Jim Watson. Here, I entered a close-knit scientific commune of extremely talented people who lived and worked together in an isolated environment for nine months, and then were immersed in a continuous scientific meeting for the remaining three summer months.

7. IBB Annual Distinguished Lectures Sharp, Phillip A. Georgia Institute of Technology. Institute for Bioengineering and Bioscience Massachusetts http://smartech.gatech.edu/handle/1853/27186

Login Register Advanced Search SMARTech Home ... IBB Annual Distinguished Lectures Browse All of SMARTech Date Author Title Subject ... Type This Collection Date Author Title Subject ... Type Control Panel Login Register Statistics View Statistics Links Help with SMARTech Policies of SMARTech About SMARTech IBB Annual Distinguished Lectures Search within this collection: Advanced Search (See All Records) Browse by Date Author Title Subject ... Type Recent Submissions 21-Sep-2010 Controlling Stem Cells McKay, Ronald D.G. Georgia Institute of Technology. Institute for Bioengineering and Bioscience Johns Hopkins University ... Lieber Institute for Brain Development Lecture, Video 02-Oct-2009 The Biology and Therapeutic Promise of Small RNAs Sharp, Phillip A. Georgia Institute of Technology. Institute for Bioengineering and Bioscience Massachusetts Institute of Technology. Koch Institute for Integrative Cancer Research Lecture, Video 16-Oct-2003 Harnessing New Technologies to Improve Health Sykes, Richard Brook Georgia Institute of Technology. Institute for Bioengineering and Bioscience Imperial College of Science, Technology, and Medicine (Great Britain) Lecture, Video 14-Nov-2002 Sustaining Growth in Medical Technology Collins, Arthur D., Jr.

8. Phillip A. Sharp Winner Of The 1993 Nobel Prize In Medicine Phillip A. Sharp, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. http://almaz.com/nobel/medicine/1993b.html

P HILLIP A S HARP 1993 Nobel Laureate in Medicine for discovery of split genes. Background Born: 1944 Residence: U.S.A. Affiliation: Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA Featured Internet Links Prize co-recipient Richard J. Roberts Search WWW Search The Nobel Prize Internet Archive Nobel News Links Let Nobelists Inspire, Menino Says Two from Mass. Win Nobel for Medicine Latest Nobel Affirms MIT Leadership in Biology Sharp Jolts MIT, Rejects Top Post (1990) Links added by Nobel Internet Archive visitors Home town reaction Biogen Winner of The Gairdner Foundation Int'l Award Phillip A. Sharp - Autobiography (submitted by Daike) Phillip A. Sharp - Nobel Lecture (submitted by Davis Brown) La rancontre des specialistes de l'ARN a Orford (submitted by alis) Phillip A. Sharp – Autobiography (submitted by Lary) Phillip A. Sharp Biography from Encyclopedia Britannica (submitted by www.britannica.com) Phillip Allen Sharp (submitted by Lukas) Back to The Nobel Prize Internet Archive Literature Peace Chemistry ... Medicine We always welcome your feedback and comments

9. Works Cited Buckler, Alan J., Chang, David D., Graw, Sharon L., Brook, J. David, Haber, Daniel A., Sharp, Phillip A., and Housman, David E. Exon amplification A strategy to isolate http://www.biochem.arizona.edu/classes/bioc461/Biochem499/AngelaPulsifer/worksci

REFERENCES 1.) Ozelius, Laurie J., Hewett, Jeffrey W., Page, Curtis E., Bressman, Susan B., Kramer, Patricia L., Shalish, Christo, de Leon, Deborah, Brin, Mitchell F., Raymond, Deborah, Corey, David P., Fahn, Stanley, Risch, Neil J., Buckler, Alan J., Gusella, James F., and Breakefield, Xandra O. "The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein" Nature Genetics , volume 17, pages 40-47 (1997). 2.) Henehan, Sean "Torsion Dystonia Gene" Access Excellence 3.) Ozelius, Laurie J., Hewett, Jeffrey, Kramer, Patricia, Bressman, Susan B., Shalish, Christo, de Leon, Deborah, Rutter,Marc, Risch, Neil, Brin, Mitchell F., Markova, Elena D., Limborska, Svetlana A., Ivanova-Smollenskaya, Irina A., McCormick, Mary Kay, Fahn, Stanley, Buckler, Alan J., Gusella, James F., and Breakefield, Xandra O. "Fine localization of the Torsion Dystonia Gene (DYT1) on Human Chromosome 9q34: Yac Map and Linkage disequilibrium" Genome Research , vol.7, pgs. 483-494 (1997).

10. Sharp Words Legal Definition Of Sharp Words. Sharp Words Synonyms By The Free On Sharp, Granville Sharp, James Sharp, Phillip A. Sharp, Phillip Allen Sharp, Principal, Diffuse, Fundamental Sharp, William Sharp, William sharpangled http://legal-dictionary.thefreedictionary.com/sharp words

11. Phillip A. Sharp (American Physiologist) -- Britannica Online Encyclopedia Phillip A. Sharp (American physiologist), June 6, 1944Falmouth, Ky., U.S.American molecular biologist, awarded the 1993 Nobel Prize for Physiology or Medicine, along with Richard J http://www.britannica.com/EBchecked/topic/538911/Phillip-A-Sharp

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12. Sharp Street United Methodist Church - What Does SSUMC Stand For? Acronyms And A Sharp, Cecil (James) Sharp, Cecil James Sharp, Granville Sharp, James Sharp, Phillip A. Sharp, Phillip Allen Sharp, Principal, Diffuse, Fundamental http://acronyms.thefreedictionary.com/Sharp Street United Methodist Church

13. Excelsior Springs Museum & Archives, Excelsior Springs, MO - Obituaries Pre-2000 Sharp , Phillip A. Sharp , Ralph D. Sharp , Retha M. Sharp , Roy . Sharp , Ruth B. Sharp , Sarah . Sharp , Sherman Daniel. Sharp , Tana . Sharp , Veldora http://www.exsmo.com/museum/obits/pre2000/pre2000s.html

email: emuseum101@hotmail.com Home Page If you would like to obtain a copy of an obituary, please review our research policy OBITUARIES Pre-2000 Volunteers at the museum have transcribed obituaries from the local newspapers, scrapbooks, and other sources. Select one of the following letters A B C D ... W X Y Z "S" Sackman , Medille B. Sadler , Guy F. Sadler , Wilmer Sagar , Helen Saintignon , Rodney Leroy Salenberg , Ruth P. Sales , Burton R. Salisbury , Howard A. Salisbury , Virgil Elvin Sallee , Jacob Daniel Salyer , Sidney E. Sambroski , Eva Marie Samples , John Victor Sams , George Wesley Sanborn , Harry W. Sandefur , Derrick T. Sanders , Caroline Christel Sanders , Chauncey Weaver Sanders , Cloyd E. Sanders , Della Ruth Sanders , George Sanders , Lester Sanders , Mary Sanders , Mary Kennedy Sanders , Rose J. Sanderson , Eric D. Sanderson , Flora E. Sanderson , Fred M. Sandidge , Hazel M. Sandoval , Joseph Raymond Sandstrom , Margaret Sandstrom , Raymond A. Sandt , John G. Sandy , Rawley S. Sarver , 34090 L.

14. Scientific Commons Phillip A. Sharp Ozanne, Brad, Sharp, Phillip A. http://en.scientificcommons.org/phillip_a_sharp

<oŽ[›J_]_½ºÇQx[¾[7tÏf�kð4z–˜¿ Võ6¬ -’Gãü9‹ <ïäÓÛŸNß½»º¨±“ÎUç-;w™ü¾Ò <K¬‹êá¦F•È ÚxÎÙ¿`�%ß ,ªXxw2QاdíðC¾‡Hˆxj%ù¾!6œVu§Dº¼$HDƒ:OÁ£ <ñÉ“eÁ¼—�ù à7`£—¼©d=ë�^gc*k�kÁd gv"Fý°Û+Ü¿×oŽÛ×o@ ÃwÄ`$„7ò"´NÏÐ:=‚]º+?V ü^¢¾Žüqª=ù3ŠE@�å²¢ µgÚá£ä?ÐÂÂïõ’‘[öŽ%V%[OÇ ˜?• <ƒI+•‡%VÃLHMEVváÞíi—s]»ø^ÁÖœ$=÷0ÅÞ-• <gykw /S^ ùÜH+‘ýÄg6Ñ�êçŸb¿ë§½ØäÆJç©SëÝΆ•´¬B�¶gÎâ,Je). <ùµÃùV«â©•Ðû¡—Ê[Þ’I�0‰mà͈hPÇ�òÍ �8¸ÀoàØ�TC ¼ˆÚ‹—æ¼’vH <ñi£›‚ <Ý Ç¶0h:=‰’ j•��µFrHMøˆû8wbßd(ÈÒ8f)üæzèÑÕŽûÑR̦—.[ß»ÜØdÝ„ ¢ ø”ºb½ì…§Ÿ¬"S[pÆ»Û8pä·¤pÞ× <ØvÝwIΠ—ªÙ)zz³±‘ ¨YÇ‘Âü¡G.E¡î'Zöí̉Ûöe°2.‰žx©—r‰±.‰0ËpÄe q$Z$Œ‡MŽ“½¼�í9ÖÆsÎþ,¤o`5Å»“‰Â <ùµÃùV«â©•Ðû¡—Ê[Þ’I�0‰mà͈hPÇ�òÍ �8¸ÀoàØ�TC eáb‹‹;eñß¹–Ñ„À,Ô«î" ®S%Ü`à°XŠ1àó <ñi£›‚ <lò~ó -Üäkþ躄7 ú£ õ™(è/›¥ IÛYñ³Š„Wbª€àÑb�½GîŠMŠ.¨DµÐ¤æc.×’Ó‚ËL´ÈÕH¡ÉÃ#

15. New Biology And Biotechnology Phil Sharp, PhD, from MIT gave a brief presentation to the Friends of the Petit Institute Group on October 2, 2009 in IBB Seminar Room 1128.......Sharp, Phillip A. http://smartech.gatech.edu/handle/1853/30612

Login Register Advanced Search SMARTech Home ... Friends of the Parker H. Petit Institute for Bioengineering and Bioscience View Item Browse All of SMARTech Date Author Title Subject ... Type This Collection Date Author Title Subject ... Type Control Panel Login Register Statistics View Statistics Links Help with SMARTech Policies of SMARTech About SMARTech New Biology and Biotechnology Show full item record Please use this identifier to cite or link to this item: http://hdl.handle.net/1853/30612 Title: New Biology and Biotechnology Author: Sharp, Phillip A. Description: Phil Sharp, PhD, from MIT gave a brief presentation to the Friends of the Petit Institute Group on October 2, 2009 in IBB Seminar Room 1128. Type: Lecture Video URI: http://hdl.handle.net/1853/30612 Date: 02-Oct-2009 Contributor: ... Massachusetts Institute of Technology. Koch Institute for Integrative Cancer Research Publisher: Georgia Institute of Technology Subject: Life sciences Societal needs Life science engineering Computational tools ... Data curation Files in this item Files Description Size Format View sharp1_streaming.html

16. Phillip A. Sharp Biography | BookRags.com World of Scientific Discovery on Phillip A. Sharp. Phillip A. Sharp has conducted research into the structure of deoxyribonucleic acid (DNA the chemical blueprint that synthesizes http://www.bookrags.com/biography/phillip-a-sharp-wsd/

17. Natural Selection Affects Frequencies Of AG And GT Dinucleotides At The 5' And 3 Fairbrother William G, Yeh RuFang, Sharp Phillip A, Burge Christopher B. Predictive identification of exonic splicing enhancers in human genes. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470862/?tool=pubmed

18. MGH Center For Systems Biology :: Investigator :: People 617643-3223, 617-643-3778 rupadhyay@mgh.harvard.edu Sharp, Phillip A., PhD http://csb.mgh.harvard.edu/investigator/ralph_weissleder/people

Center for Systems Biology People (Authorization) Faculty Devaraj, Neal, PhD ndevaraj@mgh.harvard.edu Gee, Michael, MD, PhD msgee@mgh.harvard.edu ... Shaw.Stanley@mgh.harvard.edu Ueno, Takuya, MD, PhD Ueno.Takuya@mgh.harvard.edu Weissleder, Ralph, MD, PhD rweissleder@mgh.harvard.edu Postdoctoral Fellows Budin , Ghyslain, PhD budin.ghyslain@mgh.harvard.edu Castro, Cesar, MD cmcastro@mgh.harvard.edu Chung, Jaehoon, PhD Chung.Jae-Hoon@mgh.harvard.edu Devaraj, Neal, PhD ndevaraj@mgh.harvard.edu Earley, Sarah, PhD Earley.Sarah@mgh.harvard.edu Gaglia, Jason, MD Gaglia.Jason@mgh.harvard.edu Ghazani, Arezou, PhD ghazani.arezou@mgh.harvard.edu Haun, Jered, PhD jhaun@mgh.harvard.edu Issadore, David , PhD Issadore.David@mgh.harvard.edu Karver, Mark, PhD Karver.Mark@mgh.harvard.edu Keliher, Edmund, PhD keliher.edmund@mgh.harvard.edu Liong, Monty, PhD Liong.Monty@mgh.harvard.edu Reiner, Thomas, PhD Reiner.Thomas@mgh.harvard.edu Russell, Ryan, MD Ryan.Russell@mgh.harvard.edu Thurber, Greg, PhD thurber.greg@mgh.harvard.edu Yang, Katherine, PhD yang.katherine@mgh.harvard.edu Research Assistants Morton, Angela, PhD

19. Sharp Teeth - Definition Of Sharp Teeth In The Medical Dictionary - By The Free Sharp, Cecil James Sharp, Granville Sharp, James Sharp, Phillip A. Sharp, Phillip Allen Sharp, Principal, Diffuse, Fundamental Sharp, William Sharp, William http://medical-dictionary.thefreedictionary.com/sharp teeth

20. Splicing Of Messenger RNA Precursors Title Splicing of Messenger RNA Precursors Authors Sharp, Phillip A. Publication Science, Volume 235, Issue 4790, pp. 766771 Publication Date 02/1987 http://adsabs.harvard.edu/abs/1987Sci...235..766S

Sign on SAO/NASA ADS General Science Abstract Service Find Similar Abstracts (with default settings below Electronic Refereed Journal Article (HTML) References in the article Citations to the Article (19) ... Translate This Page Title: Splicing of Messenger RNA Precursors Authors: Publication: Science, Volume 235, Issue 4790, pp. 766-771 ( Sci Homepage Publication Date: Origin: JSTOR DOI: 10.1126/science.3544217 Bibliographic Code: Abstract A general mechanism for the splicing of nuclear messenger RNA precursors in eukaryotic cells has been widely accepted. This mechanism, which generates lariat RNAs possessing a branch site, seems related to the RNA-catalyzed reactions of self-splicing introns. The splicing of nuclear messenger RNA precursors involves the formation of a multicomponent complex, the spliceosome. This splicing body contains at least three different small nuclear ribonucleoprotein particles (snRNPs), U2, U5, and U4+U6. A complex containing precursor RNA and the U2 snRNP particle is a likely intermediate in the formation of the spliceosome. Bibtex entry for this abstract Preferred format for this abstract (see Preferences Find Similar Abstracts: Use: Authors Title Abstract Text Return: Query Results Return items starting with number Query Form Database: Astronomy Physics arXiv e-prints

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