21. Spliced Early MRNAs Of Simian Virus 40 Title Spliced Early mRNAs of Simian Virus 40 Authors Berk, Arnold J.; Sharp, Phillip A. Publication Proceedings of the National Academy of Sciences of the United States of America http://adsabs.harvard.edu/abs/1978PNAS...75.1274B

Sign on SAO/NASA ADS General Science Abstract Service Find Similar Abstracts (with default settings below Electronic On-line Article (HTML) Full Printable Article (PDF/Postscript) Citations to the Article (32) ... Translate This Page Title: Spliced Early mRNAs of Simian Virus 40 Authors: Publication: Proceedings of the National Academy of Sciences of the United States of America, Volume 75, Issue 3, pp. 1274-1278 Publication Date: Origin: JSTOR Bibliographic Code: Abstract -terminal sequence. Therefore, expression of the early SV40 genes is partially controlled at the level of splicing of RNAs. Bibtex entry for this abstract Preferred format for this abstract (see Preferences Find Similar Abstracts: Use: Authors Title Abstract Text Return: Query Results Return items starting with number Query Form Database: Astronomy Physics arXiv e-prints

22. Alnylam Pharmaceuticals, Inc. (ALNY.O) Insider Trading | Reuters.com SHARP PHILLIP A Name Age Since Current Position; Clarke, John 56 2002 Chairman of the Board Maraganore, John http://www.reuters.com/finance/stocks/insiderTrading?symbol=ALNY.O&name=SHAR

23. Topic Model Browser PI SHARP, PHILLIP A. Abstract DESCRIPTION (provided by applicant) This proposal investigates the questions of the specificity and regulation of RNA splicing using bioinformatics http://datalab-1.ics.uci.edu/ninds/getdoc.php?did=34303

24. Scientific Commons Design Of TATA Box-binding Protein/zinc Finger Sharp, Phillip A., Pabo, Carl O. Abstract Fusing the TATA boxbinding protein (TBP) to other DNA-binding domains may provide a powerful way of targeting TBP to particular promoters. http://en.scientificcommons.org/18926891

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25. Phillipa Sharp: - ZoomInfo Business Information Update your professional profile, manage your online reputation or research the professional information of Phillipa Sharp at ZoomInfo.com, the most actionable professional and http://www.zoominfo.com/people/Sharp_Phillipa_1455885410.aspx

Last Update on 2/27/10 Phillipa Sharp Results found for this person at Intelius.com More results for Sharp Sharp, R. Decatur General Oncology Center Sharp, R. Decatur Orthopaedic Clinic Sharp, R. Southwest Foundation for Biomedical Research Sharp, R. Pfizer Inc Sharp, R. Buzzword , Inc. Sharp, R. Institute of Cancer Research Sharp, R.D. Fort Worth Housing Authority Sharp, R.J. Sharp Funeral Home Inc Sharp, R.L. Apostles Way International Ministries Sharp, R.P. California Institute of Technology Sharp, Rachael Hughes Fowler Carruthers View More >> Background for Phillipa Sharp Employment History University of Kent People directory A B C D ... WHAT IS ZOOMINFO?

26. Abstracts: High Affinity DNA-binding Myc Analogs: Recognition By An Alpha Helix. author Fisher, David E., Sharp, Phillip A., Parent, Lana A. Publisher Elsevier B.V. Publication Name Cell Subject Biological sciences http://www.faqs.org/abstracts/Biological-sciences/High-affinity-DNA-binding-Myc-

@import "/abstracts/css/default.css"; Abstracts search Faqs.org homepage Abstracts index Biological sciences High affinity DNA-binding Myc analogs: recognition by an alpha helix Article Abstract: The Myc oncoproteins comprise a family of DNA-binding proteins recognizing the sequence CACGTG and contain the basic helix-loop-helix and leucine zipper domains. Mutational analysis was conducted on various Myc analogs to identify critical residues in the basic region. The experiments identified a total of four amino acids which were involved in the formation of four consecutive turns of an alpha helix in the basic region. Two other conserved positions were not absolutely required for DNA binding. author: Fisher, David E., Sharp, Phillip A., Parent, Lana A. Publisher: Elsevier B.V. Publication Name: Cell Subject: Biological sciences ISSN: Year: User Contributions: Comment about this article or add new information about this topic: Comment: (50-4000 characters) Name: E-mail: Security Code: Display my email: The price of repression Article Abstract: Gene expression in eukaryotic cells is regulated by proteins that initiate gene transcription. Among the most important eukaryotic gene regulatory proteins are repressors, which repress the expression of certain genes by binding DNA sites. Repression may be active, where the repressor acts on the basal transcription machinery to prevent an isomerization by stopping the addition of new proteins to the machinery irrespective of the number of activator genes in the cell.

27. Phillip Sharp - Research Profile On BiomedExperts 2002 Fairbrother William G; Yeh RuFang; Sharp Phillip A; Burge Christopher B Predictive identification of exonic splicing enhancers in human genes. http://www.biomedexperts.com/Profile.bme/1287842/Phillip_A_Sharp

28. Phillipa Sharp, Rex Gorell: - ZoomInfo Business Information Update your professional profile, manage your online reputation or research the professional information of Phillipa Sharp, Rex Gorell at ZoomInfo.com, the most actionable http://www.zoominfo.com/people/Sharp_Phillipa_632768084.aspx

Last Update on 11/25/08 Rex Gorell Rex Gorell offer a range of products to suit your car finance needs. Please Select from the list below to find out more. Consumer Loan - Rex Gorell's Consumer... Phillipa Sharp Email Results found for this person at Intelius.com More results for Sharp Sharp, Phillipa ERM Group Inc Sharp, Phillipa University of Kent Sharp, Phoebe Long Hill Township School Systems Sharp, Phuong Intero Real Estate Services Inc Sharp, Phyllis state of texas Sharp, Polly The Hill School Sharp, Polly University of Waterloo Sharp, Polly Chateau Sharp Sharp, Portia Rio Rancho Public Schools Sharp, Preston The Stewardship Group View More >> People directory A B C D ... WHAT IS ZOOMINFO?

29. Abstracts: Dynamic Regulation Of MiRNA Expression In Ordered Stages Of Cellular author Yaffe, Michael B., Sharp, Phillip A., Chonghui Cheng. Publisher Cold Spring Harbor Laboratory Press Publication Name Genes Development http://www.faqs.org/abstracts/Biological-sciences/Dynamic-regulation-of-miRNA-ex

@import "/abstracts/css/default.css"; Abstracts search Faqs.org homepage Abstracts index Biological sciences Dynamic regulation of miRNA expression in ordered stages of cellular development Article Abstract: The discovery-compatible profiling and quantitative measurement of short RNA expression from several ordered stages of T-lymphocyte development is described. The total number of miRNA expressed per cell at different stages of development varies over nearly an order of magnitude in parallel with changes in total cellular RNA content suggesting that global miRNA levels are coregulated with the translational capacity of the cell. author: Sharp, Phillip A., Burge, Christopher B., Neilson, Joel R., Zheng, Grace X.Y. Publisher: Cold Spring Harbor Laboratory Press Publication Name: Subject: Biological sciences ISSN: Year: Gene expression, Developmental genetics, T cells User Contributions: Comment about this article or add new information about this topic: Comment: (50-4000 characters) Name: E-mail: Security Code: Display my email: A positive feedback loop couples Ras activation and CD44 alternative splicing Article Abstract: Variable exon 6 (v6)-specific small interfering RNA (siRNA) is used to investigate the role of CD44 alternative splicing in Ras signaling. A positive feedback loop is identified in which Ras signaling promotes CD44v6 splicing, and CD44v6 then sustains late Ras signaling, which is important for cell cycle progression.

30. NATIONAL MEDAL OF SCIENCE RECIPIENTS 1962-200x Sharp, Phillip A. Massachusetts Institute of Technology Starzl, Thomas E. University of Pittsburgh Medical Center Sullivan, Dennis P. City University of New York http://www.physics.ohio-state.edu/~wilkins/osu_and_ohio/medalofscience.html

NATIONAL MEDAL OF SCIENCE RECIPIENTS 1962-200x Fay Ajzenberg-Selove - University of Pennsylvania Mostafa El-Sayed - Georgia Institute of Technology Leonard Kleinrock - University of California, Los Angeles Robert Lefkowitz - Duke University Bert W. O'Malley - Baylor College of Medicine Charles P. Slichter - UIUC Andrew J. Viterbi - University of Southern California David Wineland - NIST - Boulder, CO (1989 Nobel) Bass, Hyman University of Michigan Caruthers, Marvin H. University of Colorado Colwell, Rita R. University of Maryland Dervan, Peter B. California Institute of Technology Fedoroff, Nina V. The Pennsylvania State University Kleppner, Daniel Massachusetts Institute of Technology Langer, Robert S. Massachusetts Institute of Technology Stryer, Lubert Stanford University Achenbach, Jan D. Northwestern University Alpher, Ralph A. The Dudley Observatory Bower, Gordon H. Stanford University Efron, Bradley Stanford University Fauci, MD, Anthony S. National Institutes of Health Marks, Tobin J. Northwestern University Thompson, Lonnie G. The Ohio State University

31. Phillip A. Sharp | Chemical Heritage Foundation Interview no. 0268 Interview Date January 28, 2003, May 29, 2003 and November 20, 2003 Location Massachusetts Institute of Technology, Cambridge, Massachusetts http://www.chemheritage.org/discover/collections/oral-histories/details/sharp-ph

We Tell the Story of Chemistry Chemical Heritage Foundation Visit The Othmer Library Online Catalog Quick Search ... Donate Collections Search Rare Books Oral Histories Access Levels ... New Search Phillip A. Sharp Portrait of Phillip A. Sharp Born: June 6, 1944, Falmouth, Kentucky View the Front Matter and Index of this interview Use: Semi-Restricted Order Transcript Interview Details Interview no.: Interview Date: January 28, 2003, May 29, 2003 and November 20, 2003 Location: Massachusetts Institute of Technology, Cambridge, Massachusetts Interviewers: David C. Brock, Arnold Thackray and Mona Ashiya No. of pages: Abstract of Interview Education B.A., Chemistry and Mathematics, Union College Ph.D., Chemistry, University of Illinois at Urbana-Champaign Professional Experience University of Illinois Research Assistant, Department of Chemistry California Institute of Technology Postdoctoral Fellow Cold Spring Harbor Laboratory Postdoctoral Fellow Cold Spring Harbor Laboratory Senior Research Investigator Massachusetts Institute of Technology Associate Professor, Center for Cancer Research and Department of Biology

32. Christopher Burge - Research Profile On BiomedExperts 2008 Sandberg Rickard; Neilson Joel R; Sarma Arup; Sharp Phillip A; Burge Christopher B Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA http://www.biomedexperts.com/Profile.bme/172484/Christopher_B_Burge

33. DBLP: Phillip A. Sharp 2004; 2 William G. Fairbrother, Gene W. Yeo, Rufang Yeh, Paul Goldstein, Matthew Mawson, Phillip A. Sharp, Christopher B. Burge RESCUEESE identifies candidate exonic splicing http://www.informatik.uni-trier.de/~ley/db/indices/a-tree/s/Sharp:Phillip_A=.htm

Phillip A. Sharp List of publications from the DBLP Bibliography Server FAQ Ask others: ACM DL Guide CSB MetaPress ... Matthew Mawson , Phillip A. Sharp, Christopher B. Burge : RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons. Nucleic Acids Research 32 (Web-Server-Issue): 187-190 (2004) Phillip A. Sharp: RNA biology and the genome (abstract only). RECOMB 2001 Coauthor Index Christopher B. Burge William G. Fairbrother ... Author Sat Oct 30 15:30:35 2010 by Michael Ley ley@uni-trier.de

34. MIT Office Of The Provost, Institutional Research Sharp, Phillip A. 1993 Medicine/Physiology (shared) Ting, Samuel C. C. 1976 Physics (shared) Tonegawa, Susumu 1987 Medicine/Physiology Wilczek, Frank http://web.mit.edu/ir/pop/awards/nobel.html

Nobel Prize Nobel Foundation Royal Swedish Academy of Sciences Awards and Honors Home Institutional Research Staff Home View by Relationship View by Discipline View by Year Faculty - Current: 9 Diamond, Peter A. Economic Sciences (shared) Horvitz, H. Robert Medicine/Physiology (shared) Ketterle, Wolfgang Physics (shared) Merton, Robert C.* Economic Sciences (shared) Schrock, Richard R. Chemistry (shared) Sharp, Phillip A. Medicine/Physiology (shared) Ting, Samuel C. C. Physics (shared) Tonegawa, Susumu Medicine/Physiology Wilczek, Frank Physics (shared) MIT Alumni: 20 Akerlof, George A. Economic Sciences (shared) Altman, Sidney Chemistry (shared) Annan, Kofi Peace (shared) Aumann, Robert Economic Sciences (shared) Corey, Jr., Elias J. Chemistry Cornell, Eric A. Physics (shared) Fire, Andrew Medicine/Physiology (shared) Gell-Mann, Murray Physics Hao, Wei M. Peace (one of 13 U.S. Forest Service researchers recognized under Intergovernmental Panel on Climate Change (IPCC) - shared) Hartwell, Leland H. Medicine/Physiology (shared) Klein, Lawrence R. Economic Sciences Laughlin, Robert B.

35. RasiRNA - Wikipedia, The Free Encyclopedia Repeat associated small interfering RNA (rasiRNA) is a class of small RNA that is involved in the RNA interference (RNAi) pathway. RasiRNA is a subclass of Piwiinteracting RNAs http://en.wikipedia.org/wiki/RasiRNA

RasiRNA From Wikipedia, the free encyclopedia Jump to: navigation search Repeat associated small interfering RNA (rasiRNA) is a class of small RNA that is involved in the RNA interference piRNAs ), which are small RNA molecule which interact with Piwi proteins Contents Classification RasiRNA are Distinct from other RNAi pathways RasiRNA Biogenesis Importance of rasiRNA ... edit Classification There are at least three Argonaute subfamilies that have been found in eukaryotes Drosophila and some unicellular eukaryotes but its presence in mammals has not been determined unlike piRNA which has been observed in many species of invertebrates and vertebrates including mammals Schizosaccharomyces pombe , a species of yeast, as well in some plants both of which have not been observed to contain the Piwi Argonaute protein subfamily edit RasiRNA are Distinct from other RNAi pathways RasiRNA is distinct from other RNAi pathways such as microRNA ( miRNA ) and small interfering RNA ( siRNA ) as well as from piRNA edit RasiRNA Biogenesis The ping-pong mechanism for the biogenesis of the 5' end of rasiRNA.

36. Nuclear Factors Associates With Transcriptional Regulation - Patent 5804374 Sharp, Phillip A. (Newton, MA) Singh, Harinder (Chicago, IL) Staudt, Louis (Silver Springs, MD) Lebowitz, Jonathan H. (Zionsville, IN) Baldwin Jr., Albert S. (Chapel Hill http://www.freepatentsonline.com/5804374.html

SEARCH: GO TO ADVANCED SEARCH LOGIN: Login Create Free Account HOME SEARCH PATENTS ... HELP Nuclear factors associates with transcriptional regulation United States Patent 5804374 Constitutive and tissue-specific protein factors which bind to transcriptional regulatory elements of Ig genes (promoter and enhancer) are described. The factors were identified and isolated by an improved assay for protein-DNA binding. Genes encoding factors which positively regulate transcription can be isolated and employed to enhance transription of Ig genes. In particular, NF-kB, the gene encoding NF-kB, IkB and the gene encoding IkB and uses therefor. Inventors: Baltimore, David (New York, NY) Sen, Ranjan (Cambridge, MA) Sharp, Phillip A. (Newton, MA) Singh, Harinder (Chicago, IL) Staudt, Louis (Silver Springs, MD) Lebowitz, Jonathan H. (Zionsville, IN) Baldwin Jr., Albert S. (Chapel Hill, NC) Clerc, Roger G. (Binningen, CH) Corcoran, Lynn M. (Victoria, AU) Baeuerle, Patrick A. (Eichenau, DE)

37. 20th Century Year By Year 1993 Great Britain, New England Biolabs, Beverly, MA, U.S.A., b. 1943; and SHARP, PHILLIP A., U.S.A., Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, b http://www.historycentral.com/20th/1993.html

38. Sharp V Thread Definition Of Sharp V Thread In The Free Online Encyclopedia. sharp tuning sharp V thread Sharp, Cecil James Sharp, Granville Sharp, James Sharp, Phillip A. Sharp, William sharpcrested weir sharp-cutoff tube http://encyclopedia2.thefreedictionary.com/sharp V thread

39. PDCD2 - Wikipedia, The Free Encyclopedia Programmed cell death protein 2 is a protein that in humans is encoded by the PDCD2 gene. This gene encodes a nuclear protein expressed in a variety of tissues. http://en.wikipedia.org/wiki/PDCD2

From Wikipedia, the free encyclopedia Jump to: navigation search This article is an orphan , as few or no other articles link to it . Please introduce links to this page from related articles suggestions may be available (February 2009) edit Programmed cell death 2 Identifiers Symbols External IDs OMIM MGI HomoloGene GeneCards ... Gene Ontology Molecular function DNA binding protein binding zinc ion binding metal ion binding Cellular component nucleus cytoplasm Biological process apoptosis Sources: Amigo EGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 6: 170.73 - 170.74 Mb Chr 17: 15.23 - 15.23 Mb ... PubMed search Programmed cell death protein 2 is a protein that in humans is encoded by the gene This gene encodes a nuclear protein expressed in a variety of tissues. The rat homolog, Rp8, is transiently expressed in immature thymocytes and is thought to be involved in programmed cell death. Expression of the human gene has been shown to be repressed by BCL6, a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on PDCD2. This gene is closely linked on chromosome 6 to the gene for TBP, the TATA binding protein. Two transcripts encoding different proteins have been identified. edit Interactions PDCD2 has been shown to interact with Host cell factor C1 and Parkin (ligase) edit References Kawakami T, Furukawa Y, Sudo K, Saito H, Takami S, Takahashi E, Nakamura Y (Aug 1995). "Isolation and mapping of a human gene (PDCD2) that is highly homologous to Rp8, a rat gene associated with programmed cell death".

40. Sharp Tongue - Idioms - By The Free Dictionary, Thesaurus And Encyclopedia. Sharp, Cecil James Sharp, Granville Sharp, James Sharp, Phillip A. Sharp, Phillip Allen Sharp, Principal, Diffuse, Fundamental Sharp, William Sharp, William http://idioms.thefreedictionary.com/sharp tongue

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