Roger Charles Louis Guillemin — FactMonster.com Encyclopedia Guillemin, Roger Charles Louis. Guillemin, Roger Charles Louis (gēy u măN') , 1924–, FrenchAmerican physiologist, b. Dijon, France. http://www.factmonster.com/ce6/people/A0822102.html
Extractions: Reference Desk Encyclopedia Guillemin, Roger Charles Louis u key endorphins , a class of hormonal substances. His work added new dimensions to the study of the brain's control over the body's chemistry. In 1977, Guillemin shared the Nobel Prize in Physiology or Medicine with Andrew Schally and Rosalyn Yalow The Columbia Electronic Encyclopedia, Atlas ... Encyclopedia Click Here! Click Here! 24 x 7 Tutor Availability Unlimited Online Tutoring 1-on-1 Tutoring Explore Solving Equation Math Helper Contact Us Advertise with Fact Monster ... Privacy
Facts About Guillemin, Roger, As Discussed In Britannica Compton's Encyclopedia Facts about Guillemin, Roger, (born 1924), U.S. physiologist, born in Dijon, France; to U.S. 1953, naturalized 1965; professor Baylor College of Medicine, Houston, 1953–70 http://www.britannica.com/facts/11/916196/Guillemin-Roger-as-discussed-in-Guille
Extractions: document.write(''); Search Site: With all of these words With the exact phrase With any of these words Without these words Home Did you know... (born 1924), U.S. physiologist, born in Dijon, France; to U.S. 1953, naturalized 1965; professor Baylor College of Medicine, Houston, 1953–70; at Salk Institute and University of California, San Diego, 1970–; received 1977 Nobel prize for research on hormone production in the brain. see also in index Nobel Prizewinners, Get Random Facts Britannica Content: Other Britannica sites: Australia France India Korea ... SHARE Save to My Workspace Submit an image to Britannica Submit a video to Britannica All of the media associated with this article appears on the left. Click an item to view it.
McGraw-Hill's AccessScience About AccessScience. AccessScience is a subscriptionbased website that features continually updated scientific and http://www.accessscience.com/content.aspx?searchStr=Radioimmunoassay&id=M009
Roger Charles Louis Guillemin — Infoplease.com More on Roger Charles Louis Guillemin from Infoplease Guillemin meaning and definitions Guillemin Definition and Pronunciation; See more Encyclopedia articles on http://www.infoplease.com/ce6/people/A0822102.html
Guillemin, Roger Charles Louis Guillemin, Roger Charles Louis (b. Jan. 11, 1924, Dijon, Fr.), Frenchborn American physiologist whose researches into the hormones produced by the hypothalamus gland resulted in http://www.uv.es/EBRIT/micro/micro_250_65.html
Extractions: Britannica CD Index Articles Dictionary Help (b. Jan. 11, 1924, Dijon, Fr.), French-born American physiologist whose researches into the hormones produced by the hypothalamus gland resulted in his being awarded a share (along with Andrew Schally and Rosalyn Yalow) of the Nobel Prize for Physiology or Medicine in 1977. Among Guillemin's achievements were the isolation of the first hypothalamic hormone to be discovered, TRH ( thyrotropin -releasing hormone); the isolation and synthesis of somatostatin , a hypothalamic hormone that regulates activities of the pituitary gland and the pancreas; and the discovery of a new class of hormonal substances called endorphins. Related Propaedia Topics: The Structures and Functions of Organisms
Roger Charles Louis Guillemin Nobel Winners picture, Nobel Winners Bio Roger Charles Louis Guillemin (1924) Frenchborn American physiologist whose researches into the hormones produced by the http://www.nobel-winners.com/Medicine/roger_charles_louis_guillemin.html
Extractions: Guillemin was educated at the universities of Dijon, Lyon, and Montreal. He taught at the Baylor College of Medicine in Houston, Texas, from 1953 to 1970, except for the years 1960-63, when he was on the faculty of the College de France in Paris. From 1970 he was a resident fellow and research professor at the Salk Institute for Biological Studies in La Jolla, Calif. Guillemin became a U.S. citizen in 1963. Guillemin proved the hypothesis that the hypothalamus releases hormones that regulate the pituitary gland. Among the hypothalamic hormones that he and his colleagues discovered, isolated, analyzed, or synthesized were TRH (thyrotropin-releasing hormone), which regulates thyroid activity; GHRH (growth hormone-releasing hormone), which causes the pituitary to release gonadotropin; and somatostatin, which regulates the activities of the pituitary gland and the pancreas. Guillemin also discovered an important class of proteins called endorphins that are involved in the perception of pain.
Roger Guillemin: Biography From Answers.com (born Jan. 11, 1924, Dijon, Fr.) Frenchborn U.S. physiologist. He and his colleagues discovered, isolated, and synthesized hypothalamic hormones that regulate thyroid http://www.answers.com/topic/guillemin-roger-charles-louis
Guillemin, Roger Charles Louis Frenchborn US endocrinologist. He has isolated and identified various hormones, for which he received the 1977 Nobel Prize for Physiology or Medicine, together http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/G/Guillemin/1.ht
Extractions: Guillemin found that the brain controls the pituitary gland by means of hormones produced by central neurons - the neurosecretory cells of the hypothalamus. He worked with Lithuanian refugee Schally 1957-62, and later their investigations were parallel. Between 1968 and 1973 they isolated and synthesized three hypothalamic hormones which regulate the secretion of the anterior pituitary gland.
Roger Charles Louis Guillemin (American Physiologist) -- Britannica Online Encyc Facts about Guillemin, Roger, as discussed in Britannica Compton's Encyclopedia Guillemin, Roger When was Roger Charles Louis Guillemin born? Where was Roger Charles Louis Guillemin http://www.britannica.com/EBchecked/topic/248741/Roger-Charles-Louis-Guillemin
Extractions: document.write(''); Search Site: With all of these words With the exact phrase With any of these words Without these words Home My Britannica CREATE MY Roger Charle... NEW ARTICLE ... SAVE Table of Contents: Roger Charles Louis Guillemin Article Article Additional Reading Additional Reading Supplemental Information Supplemental Information - Spotlights Spotlights External Web sites External Web sites Citations ARTICLE from the Roger Charles Louis Guillemin (b. Jan. 11, 1924, Dijon, France), French-born American physiologist whose researches into the hormones produced by the hypothalamus gland resulted in his being awarded a share (along with Andrew Schally and Rosalyn Yalow ) of the Nobel Prize for Physiology or Medicine in 1977.
Roger | Define Roger At Dictionary.com –interjection 1. Informal . all right; O.K. 2. message received and understood (a response to radio communications). 3. ( often initial capital letter ) Jolly Roger. 4 http://dictionary.reference.com/browse/roger
Ten Nobels For The Future Guillemin, Roger C.L. Medicine, 1977 Hoffmann, Roald Chemistry, 1981 Jacob, Fran ois Medicine, 1965 Kindermans, JeanMarie Peace 1999 http://www.hypothesis.it/nobel/eng/bio/guillemin.htm
Gonadostatin Ling, Nicholas C.; Guillemin, Roger C. L.; Ying, ShaoYao; Esch, Frederick S.; A substantially purified substance has been isolated from bovine gonadal http://www.devileye.net/catalog/dental_x-ray_duplicator/gonadostatin.html
Extractions: Ling, Nicholas C.; Guillemin, Roger C. L.; Ying, Shao-Yao; Esch, Frederick S.; A substantially purified substance has been isolated from bovine gonadal secretions which mediates pituitary hormone secretion, using an extraction and purification sequence that includes gel filtration, partition chromatography and HPLC in that order. The substance, designated gonadostatin, is a moderate-size peptide which below a threshold level selectively inhibits LRF-stimulated pituitary secretion of LH and FSH. Above a threshold level, gonadostatin generally stimulates pituitary hormone secretion. The present invention relates to peptides which influence the release of hormones by the anterior pituitary gland. A substantially pure substance, which is primarily protein in nature, has been isolated from mammalian seminal plasma. The substance, designated gonadostatin, selectively inhibits LRF-induced secretions of FSH and LH and has a molecular weight of about 11,000, as measured by gel filtration. The purification of gonadostatin is achieved by gel filtration, followed by partition chromatography, followed by reverse-phase high performance liquid chromatography (HPLC), with selection of fractions exhibiting gonadostatin activity at each step. In accordance with the present invention, a substance, designated gonadostatin, has been isolated from bovine seminal plasma (BSP) which according to HPLC and N-terminal analysis criteria shows a purity greater than 99% by weight. When added to an in vitro culture of rat anterior pituitary cells, gonadostatin, in concentrations of up to about 50 .mu.g/ml., inhibits LRF-induced pituitary secretion of LH and FSH. Higher doses of gonadostatin generally promote the secretion of pituitary hormones including LH, FSH and TSH.
DNA Encoding Follistatin Ling, Nicholas C. K.; Ueno, Naoto; Shimasaki, Shunichi; Esch, Frederick S.; Ying, ShaoYao; Guillemin, Roger C. L.; http://www.devileye.net/catalog/clamping_terminal_unit/dna_encoding_follistatin.
Extractions: Ling, Nicholas C. K.; Ueno, Naoto; Shimasaki, Shunichi; Esch, Frederick S.; Ying, Shao-Yao; Guillemin, Roger C. L.; The present invention relates to a protein having inhibin-like activity isolated substantially to homogeneity from bodily material obtained from porcine animals and which is referred to as follistatin. In accordance with the present invention, two proteins, one having a molecular weight of about 35,000 daltons (35K) and the other about 32,000 daltons (32K) and both having inhibin activity have been successfully isolated from porcine follicular fluid. These two proteins have been completely characterized using microsequencing and molecular biological methods. Using the porcine amino acid sequence information, cDNA clones encoding these proteins were identified from a porcine ovarian cDNA library. Then, using the porcine cDNA as a probe, the cloning and sequencing of the corresponding human and rat proteins were accomplished. More specifically, the proteins were first isolated and purified to substantial homogeneity from material obtained from the bodies of porcine animals and are hereinafter referred to as Follistatin A and Follistatin B. Each protein is composed of a single polypeptide chain. Microsequencing showed that the amino-terminal amino acid residue sequence of both proteins was Gly-Asn-Cys-Trp-Leu-Arg-Gln-Ala-Lys-Asn-Gly-Arg-Cys-Gln-Val-Leu. It was also ascertained that the next eight residues of Follistatin A were Tyr-Lys-Thr-Glu-Leu-Ser-Lys-Glu. Follistatin A has now been completely characterized as a result of further microsequencing and the use of molecular biological techniques. Each protein exhibits inhibin-like activity in that it specifically inhibits basal secretion of FSH but does not inhibit basal secretion of luteinizing hormone (LH).
