Sakmann, Bert Sakmann, Bert (b. June 12, 1942, Stuttgart, Ger.), German medical doctor and research scientist who in 1991, together with German physicist Erwin Neher, won the Nobel Prize for http://www.uv.es/EBRIT/micro/micro_519_58.html
Extractions: Britannica CD Index Articles Dictionary Help (b. June 12, 1942, Stuttgart, Ger.), German medical doctor and research scientist who in 1991, together with German physicist Erwin Neher , won the Nobel Prize for Physiology or Medicine for research into basic cell function and for their development of the patch -clamp techniquea laboratory method widely used in cell biology and neuroscience to detect electrical currents as small as a trillionth of an ampere through cell membranes. Working together they conclusively established the existence of characteristic sets of ion channels in cell membranessome of which permit the flow of only positive ions, while others pass only negatively charged ions. This established, they examined a broad range of cellular functions, eventually discovering the role that ion channels play in such diseases as diabetes, cystic fibrosis, epilepsy, several cardiovascular diseases, and certain neuromuscular disorders. These discoveries enabled the development of new and more specific drug therapies. In 1979 Sakmann became a research associate in the Max Planck Institute's membrane biology group. He was made head of the membrane physiology unit in 1983, and he became director of the institute's department of cell physiology two years later.
Bert Sakmann — Infoplease.com More on Bert Sakmann from Infoplease Edwin Neher Neher, Edwin Neher, Edwin, 1944–, German biophysicist, Ph.D. Technical Univ. of Munich, 1970. http://www.infoplease.com/ce6/people/A0935443.html
Bert Sakmann (German Scientist) -- Britannica Online Encyclopedia Facts about Sakmann, Bert, as discussed in Britannica Compton's Encyclopedia Sakmann, Bert When was Bert Sakmann born? Where was Bert Sakmann born? http://www.britannica.com/EBchecked/topic/518742/Bert-Sakmann
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Extractions: mboxCreate('TT_Global_Mbox','pageName='+window.s.pageName, 'retCust=no', 'profile.retCust=no'); Sign In Rental Cart ( CHEGG.COM FIND YOUR BOOKS FIND BOOKS SEARCH TIPS x Search Tip: The best way to find your books is by searching using ISBNs. Alternatively, you can also search using book title or author's name. But better results are returned when you put in book title and one of the authors' name together. Here are some examples of good searches: Home Science Life Sciences by ISBN: EDITION: 2 Edition Type: Revised BINDING: PUBLISHER: Springer (05/31/1995) PAGES: This product is not available. SUMMARY Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping. SUMMARY Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipet...
Extractions: Each year, the Louisa Gross Horwitz Prize has been awarded by Columbia University for outstanding basic research in the fields of biology or biochemistry The purpose of this prize is to honor a scientific investigator, or group of investigators, whose contributions to knowledge in either of these fields are deemed worthy of special recognition. Previous Prize Awardees
Dr. Bert Sakmann | Research Groups | Max Planck Florida Institute Dr. Bert Sakmann INAUGURAL SCIENTIFIC DIRECTOR AND RESEARCH GROUP LEADER. Dr. Sakmann, with physicist Erwin Neher, was awarded the Nobel Prize in Medicine in 1991 for their http://www.maxplanckflorida.org/bert-sakmann.html
Extractions: About Us Research Groups Lectures Press Room ... Community Dr. Sakmann, with physicist Erwin Neher, was awarded the Nobel Prize in Medicine in 1991 for their discoveries on single channels in cells, enabled by their invention of the patch-clamp technique. This ground-breaking technical achievement made it possible to examine, in real time, the operation of individual ion channel proteins. Ion channels are found in the membranes of virtually all cells and create selective pores across membranes that are vital for electrical signaling. Sakmann and Neher examined a broad range of cellular functions, eventually discovering the role that ion channels play in diseases such as diabetes, cystic fibrosis, several cardiovascular diseases and certain neuromuscular disorders. This technique forged new paths in the study of membrane physiology and the creation of novel therapeutics targeting ion channels. In fact, the Nobel Prize committee credited the two scientists with revolutionizing modern biology. Research of the Digital Neuroanatomy group focuses on functional anatomy of circuits in the brain – specifically the cerebral cortex – that form the basis of simple behaviors (e.g. decision making). This research involves the use of large scale, high resolution microscopic techniques to reconstruct individual morphologies, distributions and synaptic wiring of different neuron types. Neurons are recorded from using in vivo and in vitro electrophysiological techniques. The results are used to simulate signal flow in an anatomically realistic network model. Eventually, this may reveal parts of the network that trigger sensory initiated behavior and lead to new discoveries about the brain's process of learning.
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Bert Sakmann Bert Sakmann. Born 12Jun-1942 Birthplace Stuttgart, Germany. Gender Male Race or Ethnicity White Sexual orientation Straight Occupation Scientist, Doctor http://www.nndb.com/people/861/000133462/
Extractions: Executive summary: Cellular ion channels German physiologist Bert Sakmann won the Nobel Prize for Medicine in 1991, for describing "the function of single ion channels in cells." Working with Erwin Neher , his long-time collaborator and co-winner of Nobel honors, Sakmann invented the patch clamp, which allows observation of the minute electrical energy produced in cellular ion channels. His wife was a prominent pediatric ophthalmologist, and as Sakmann toiled in obscurity early in his career, he said he was sometimes better known as "the eye doctor's husband". Father: Bertold Sakmann (theater director)
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Extractions: OR Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping. top Related News for Single-Channel Recording FIRST PRESENTERS ANNOUNCED FOR "THE 44TH ANNUAL CMA AWARDS," WEDNESDAY, NOVEMBER 10 ON THE ABC TELEVISION NETWORK (October 26)
Extractions: JSTOR Bibliographic Code: Abstract By the combination of cDNA manipulation and functional analysis of normal and mutant acetylcholine receptor (AChR) channels of Torpedo expressed in Xenopus laevis oocytes determinants of ion flow were localized in the bends bordering the putative M2 transmembrane segment (Imoto et al. 1988). We now report that in the rat muscle AChR, substitution of a threonine residue in the alpha -subunit localized in the M2 transmembrane segment increases or decreases the channel conductance, depending on the size of the amino acid side chain located at this position. This threonine residue (alpha T264) is located adjacent to the cluster of charged amino acids that form the intermediate anionic ring (Imoto et al. 1988). This effect is pronounced for the large alkali cations Cs , Rb , K whereas for Na the effect is much smaller. Taken together the results suggest that the threonine residues at position 264 in the two alpha -subunits together with the amino acids of the intermediate anionic ring form part of a narrow region close to the cytoplasmic mouth of the AChR channel.
Sakmann, Bert - Personenlexikon Enter your search terms Submit search form Top International Italiano Salute Medicina Medici e Ricercatori Sakmann, Bert http://www.personenlexikon.net/d/sakmann-bert/sakmann-bert.htm
Extractions: Startseite Personenlexikon Thematische Gliederung Gruppen Kategorien ... Z deutscher Mediziner, geboren 12.6.1942 Stuttgart; ab 1985 Direktor der Abteilung für Zellphysiologie des MPI-Instituts für biophysikalische Chemie in Göttingen, ab 1989 am MPI für medizinische Forschung in Heidelberg; erforschte in den 70er Jahren in Göttingen zusammen mit E. s Neher Ionenkanäle und erhielt zusammen mit Neher für die Entwicklung der patch-clamp-Methode (zur Messung der äußerst schwachen Ionenkanal-Ströme) 1991 den Nobelpreis für Physiologie oder Medizin. Diese Seite als Bookmark speichern : addthis_url = location.href; addthis_title = document.title; addthis_pub = 'woorgle1492'; Sainte-Claire Deville, Henri Étienne Salam, Abdus Weitere Begriffe : Empedokles, griechischer Naturphilosoph und Wanderarzt Buys-Ballot, Christophorus Henricus Didericus Rutherford, Ernest Personenlexikon Neuen Artikel hinzufügen Rechtliche Hinweise Impressum der Bände, »Antibiotika-Fibel« (9. sur chimiques 1832 übergegangen) (9. des Harrison, John
Erwin Neher: Facts, Discussion Forum, And Encyclopedia Article Landsberg am Lech is a town in southwest Bavaria, Germany, about 65 kilometers west of Munich and 35 kilometers south of Augsburg. It is the capital of the district of Landsberg am http://www.absoluteastronomy.com/topics/Erwin_Neher
Extractions: Home Discussion Topics Dictionary ... Login Erwin Neher Overview Erwin Neher (born 20 March 1944 in Landsberg am Lech Landsberg am Lech Landsberg am Lech is a town in southwest Bavaria, Germany, about 65 kilometers west of Munich and 35 kilometers south of Augsburg. It is the capital of the district of Landsberg am Lech.... ) is a German Germany Germany , officially the Federal Republic of Germany , is a country in Central Europe. It is bordered to the north by the North Sea, Denmark, and the Baltic Sea; to the east by Poland and the Czech Republic; to the south by Austria and Switzerland; and to the west by France, Luxembourg, Belgium,... biophysicist Biophysics Biophysics is an interdisciplinary science that uses the methods of physics and physical chemistry to study biological systems. Studies included under the branches of biophysics span all levels of biological organization, from the molecular scale to whole organisms and ecosystems...
Bert Sakmann - Research Profile On BiomedExperts 2006 Hahn Thomas T G; Sakmann Bert; Mehta Mayank R Phaselocking of hippocampal interneurons' membrane potential to neocortical up-down states. http://www.biomedexperts.com/Profile.bme/1228097/Bert_Sakmann
Scientific Commons Otto D. Creutzfeldt An experimental comparison between the ganglion cell receptive field and the receptive field of the adaptation pool in the cat retina (1969) Sakmann,Bert http://en.scientificcommons.org/otto_d_creutzfeldt