Tonegawa, Susumu Tonegawa, Susumu (1939) I was born in Nagoya, Japan on September 6th, 1939, the second of three sons. I have also a younger sister. http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/T/Tonegawa/Toneg
Extractions: Tonegawa, Susumu I was born in Nagoya, Japan on September 6th, 1939, the second of three sons. I have also a younger sister. My father was an engineer working for a textile company that had several factories scattered in rural towns in the southern part of Japan. The company policy made it necessary for my father to move from one factory to another every few years. I and my brothers and sister spent most of our childhood in these small provincial towns, enjoying the space and freedom of the countryside. As my elder brother and I reached adolescence, however, my parents decided to send us to Tokyo so that we could receive a better education. I commuted to the prestigious Hibiya high school from my Uncle's home in Tokyo. During the high school years I developed an interest in chemistry, so upon graduation, I chose to take an entrance examination for the Department of Chemistry of the University of Kyoto, the old capital of Japan. After having failed once, I was admitted to this University in 1959. This happened to be one year before the first ten-year term of the defence treaty between Japan and the United States expired and the governments of both countries were preparing for a second ten-year term. The nation was deeply divided between the pragmatic pro-American conservatives and the idealistic anti-military leftists. Being the home of the most radical leftist student groups, classes at Kyoto University were often cancelled due to frequent political discussions and demonstrations on the streets. I was only a passive participant, withdrawn from the turmoil, but could not help having a feeling of defeat shared with many of my classmates when the treaty was finally extended for the next ten-year term. I believe that this experience might have been a major factor in making me give up the original goal of becoming a chemical engineer to pursue the academic life.
MIT Department Of Biology: Susumu Tonegawa Overview Our primary research interests are the molecular, cellular, and neuronal circuitry mechanisms underlying acquisition, consolidation, and http://web.mit.edu/biology/www/facultyareas/facresearch/tonegawa.html
Extractions: Memory acquisition. Using the Cre/loxP system, we previously targeted a knockout of the obligatory N-methyl-D-aspartate (NMDA) receptor (NR) subunit, NR1, to the CA1 pyramidal cells of young adult mice. (Tsien et al. , 1996b) These mice displayed impairments in the Schaffer collateral (SC) CA1 long-term potentiation (LTP) and in spatial learning in the standard Morris water maze task. That this mutant mouse is defective in the acquisition rather than the retrieval of the memory was suggested by its inability to form normal memory representations as CA1 place cells (McHugh et al. , 1996). These findings remain the most cogent single evidence for the hypothesis that synaptic plasticity underlies memory. Memory Consolidation.
Tonegawa Susumu: Information From Answers.com Tonegawa Susumu Japanese molecular biologist noted for his studies of how the immune system produces antibodies (born in http://www.answers.com/topic/tonegawa-susumu
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What Does Tonegawa Susumu Mean? Definition of tonegawa susumu in the Definitions.net dictionary. Meaning of tonegawa susumu. What does tonegawa susumu mean? Information and translations of tonegawa susumu in the http://www.definitions.net/definition/tonegawa susumu
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Tonegawa Susumu Tonegawa Susumu (b. Sept. 5, 1939, Nagoya, Japan), Japanese molecular biologist and immunologist who was awarded the Nobel Prize for Medicine or Physiology in 1987 for his http://www.uv.es/EBRIT/micro/micro_598_42.html
Extractions: Britannica CD Index Articles Dictionary Help (b. Sept. 5, 1939, Nagoya, Japan), Japanese molecular biologist and immunologist who was awarded the Nobel Prize for Medicine or Physiology in 1987 for his fundamental discoveries concerning the body's production of antibodies Tonegawa received a B.S. degree from Ky o to University in 1963 and earned a Ph.D. in biology from the University of California at San Diego in 1969. He was a member of the Basel Institute for Immunology in Switzerland from 1971 to 1981 and taught biology at the Massachusetts Institute of Technology from 1981. Tonegawa's research explained how the immune system can produce a vast diversity of antibodies, each of which reacts with and counteracts the effects of a separate antigen (a foreign molecule or microbe). Prior to Tonegawa's work it was not known how the B lymphocytes (the cells that produce antibodies) could with their limited number of genes produce the millions of differently structured antibodies that are specific to a comparable diversity of antigens. In the 1970s Tonegawa proved in a series of experiments that approximately 1,000 pieces of genetic material in the antibody-manufacturing portion of the B lymphocyte can be shuffled or recombined into different sequences, the resulting variations enabling the production of as many as one billion different types of antibodies, each specific to a different antigen. A fundamental mechanism in the immune system was thus revealed.
Susumu Tonegawa — FactMonster.com More on Susumu Tonegawa from Fact Monster Information Please 1987 1987 Previous Year Next Year World U.S. Economics Sports Entertainment Science Deaths http://www.factmonster.com/ce6/people/A0849023.html
NETBible: Tonegawa Susumu WORDNET DICTIONARY Noun tonegawa susumu has 1 sense. tonegawa susumu (n = noun.person) Japanese molecular biologist noted for his studies of how the immune system produces http://net.bible.org/lexicon.php?word=tonegawa susumu
Tonegawa Lab A Nobel Laureate’s Stealthy Biotech, Its Japanese Pharma Backer, and the Englishman In Charge Outside of certain circles at MIT, you’d be hard pressed to find someone who is http://www.tonegawalab.org/
Extractions: Please click hereclick here to view the flyer for the "From Molecular Biology to Immunology and Neuroscience: A Journey of ... Outside of certain circles at MIT, you’d be hard pressed to find someone who is familiar with the biotech startup ... By examining how we learn and store memories, Australian and American scientists have uncovered a new mechanism of learning that might prove useful in ... CAMBRIDGE, Mass. — Neuroscientists at MIT and Tsinghua University in Beijing show that increasing brain magnesium with a new compound ... Researchers at the Picower Institute for Learning and Memory at MIT report in the Jan. 24 online edition of Science ...