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Gene Therapy: more books (100)

Vascular Embolotherapy: A Comprehensive Approach, Volume 2: Oncology, Trauma, Gene Therapy, Vascular Malformations, and Neck (Medical Radiology / Diagnostic Imaging)
Gene Therapy (Ernst Schering Foundation Symposium Proceedings)
Progress in Gene Therapy: Pioneering Stem Cell/Gene Therapy Trials
Tumor Suppressing Viruses, Genes, and Drugs: Innovative Cancer Therapy Approaches
Gene Therapy and Ethics (Acta Universitatis Upsaliensis: Studies in Bioethics & Research Ethics, 4)
The 2009 Report on Gene Therapy: World Market Segmentation by City by Icon Group International, 2009-07-06
30th Hemophilia Symposium Hamburg 1999: HIV Infection and Epidemiology in Hemophilia; Gene Therapy in Hemophilia A and B; Therapy of Hepatitis C; Inhibitors ... Pediatric Hemostasiology; Case Reports
Gene Therapy for Neurological Disorders & Brain Tumors (Contemporary Neuroscience)
Cancer Gene Therapy: Past Achievements and Future Challenges
The 2009-2014 Outlook for Gene Therapy in Greater China by Icon Group International, 2009-07-07
The 2009-2014 Outlook for Gene Therapy in The Middle East & Africa by Icon Group International, 2009-05-29
Gene Therapy in Cancer (Basic and Clinical Oncology)
The 2009-2014 Outlook for Gene Therapy in Europe by Icon Group International, 2009-05-28
The promise of gene therapy.(Guest Editorial): An article from: Pediatric News by Joseph C., III Glorioso, 2004-03-01

lists with details

AMA - Gene Therapy
The Therapy Treated A Fouryear-old Child For Adenosine Deaminase (ADA) Deficiency, A Rare Genetic Disease In Which Children Are Born With Severe Immunodeficiency And Are Prone
http://www.ama-assn.org/ama/pub/physician-resources/medical-science/genetics-mol
Treatment For Parkinson's, Treatment For Alzheimer's
Pioneering genetic therapies for neurologic disorders.
http://www.ceregene.com
NHF | Bleeding Disorders Information Center | Gene Therapy: General Information
Gene Therapy Pages gene therapy (main) gene therapy FAQ gene therapy articles gene therapy trials Gene Therapy Gene therapy represents a new field of medicine, one which can
http://www.hemophilia.org/bdi/bdi_gene.htm

Extractions: Gene therapy represents a new field of medicine, one which can potentially cure many genetic diseases such as bleeding disorders. Patients with inherited diseases such as hemophilia usually lack a functional protein, which can be replaced with periodic protein replacement therapy. An alternative is to add a normal gene to substitute for the defective one. The normal gene, if delivered to the right cells and in sufficient quantity, can continuously make the normal version of the defective protein, restoring normal clotting mechanisms. However, this is a new and highly experimental field. Many questions remain unanswered and will only be answered through a series of clinical studies, some of which are ongoing using the genes for factors VIII and IX. There have been many failures and disapointments when investigators have found that the technology for delivering the genes was inadequate when used in humans. Sometimes investigators have underestimated the complexity of the diseases they were attempting to cure. Because of some recent successes, hemophilia has emerged as the top candidate for a genetic disease most likely to benefit from gene therapy.
Gene Therapy Research Unit - The Children's Hospital At Westmead
A joint initiative of The New Children s Hospital and the Children s Medical Research Institute is undertaking gene therapy clinical trials in Australia. Research projects include cancer immunotherapy, vector development, HIV infection, targeting gene delivery to specific tissue types.
http://www.chw.edu.au/prof/services/genetherapy/

Extractions: feedback sitemap gap for health telehealth ... Gene Therapy Research Unit A joint initiative of The Children's Hospital at Westmead and Children's Medical Research Institute Main Projects Publications Staff Contact The ultimate aim of biomedical research is to improve human health, but its more immediate impact, beyond the accumulation of biological knowledge, is an increase in our capacity to diagnose disease. Therapeutic benefits follow, but significantly more slowly. Herein lies a potentially frustrating paradox. When biomedical knowledge is undergoing rapid growth (as it is at present) we can anticipate a widening of the gap between our capacity to diagnose and our capacity to treat disease. For this reason it is fundamentally important that increased effort be focused on realising the therapeutic potential of advances in biological knowledge. Such an effort demands that we explore entirely new therapeutic paradigms and surmount the formidable translational challenges inherent in taking new therapies from the laboratory bench to the patient bedside. Gene Therapy, or "the use of genes as medicine" is one such paradigm, with immense but largely unrealised potential. The Gene Therapy Research Unit, a joint initiative of the The Children's Hospital at Westmead and
Alberta Gene Therapy Group
A network of researchers looking to foster collaboration in several therapeutic fields.
http://www.ualberta.ca/~britchie/agtg.html
Gene Therapy Ppt Presentation
Gene Therapy is a new modality of medical Technology can be utilized in several disorders, A better understanding of the conseq.. A PowerPoint presentation
http://www.authorstream.com/Presentation/doctorrao-210228-gene-therapy-entertain
Vektorologie Und Experimentelle Gentherapie - Startseite
Group researching adenovirus-based approaches for the delivery of anti-cancer genes.
http://www.gentherapie.med.uni-rostock.de/
Gene Therapy
Clinical gene transfer had its official beginning when, in 1989, 5 patients with terminal melanoma were given autologous lymphocytes that had been marked ex vivo with a gene
http://focosi.altervista.org/genetherapy.html

Extractions: Principles of gene therapy Web resources Clinical gene transfer had its official beginning when, in 1989, 5 patients with terminal melanoma were given autologous lymphocytes that had been "marked" ex vivo with a gene encoding resistance to the antibiotic G418. This study was designed primarily to trace the cells in the patients' bodies and to show the safety of gene transfer, and in that sense it was successful. No helper viruses were found, no reverse transcriptase activity was detected, no toxicity was experienced, and the transduced cells remained otherwise "normal" ref Principles of gene therapy Gene therapy consists of altering cell genotype by transfecting polynucleotides ... ... directly into body cells ( in vivo gene therapy ... into cells extracted, cultured in vitro , transfected, selected (also against deleterious insertional mutagenesis !) and then re-inserted into the donor's body ( ex vivo gene therapy , sometimes wrongly called in vitro gene therapy) : please note that not all cell types can be extracted from the body (e.g. neurons) and/or cultured
Types Of Treatment - Gene Therapy - MD Anderson Cancer Center
The human cancer gene prevention and therapy program conducts basic research, clinical trials and vector development.
http://www.mdanderson.org/patient-and-cancer-information/cancer-information/canc

Extractions: Skip to Content Keyword Much of today's cancer research is devoted to finding missing or defective genes that cause cancer or increase an individual's risk for certain types of cancer. Gene research at MD Anderson has resulted in many important discoveries. We identified the mutated multiple advanced cancers gene (MMAC1) involved in some common cancers. We also performed the first successful correction of a defective tumor suppressor gene (p53) in human lung cancer. Current gene therapies are experimental, and many are still tested only on animals. There are some clinical trials involving a very small number of human subjects. The potential benefits of gene therapy are two-fold: The focus of most gene therapy research is the replacement of a missing or defective gene with a functional, healthy copy, which is delivered to target cells with a "vector." Viruses are commonly used as vectors because of their ability to penetrate a cell’s DNA. These vector viruses are inactivated so they cannot reproduce and cause disease. Gene transfer therapy can be done outside the body (ex vivo) by extracting bone marrow or blood from the patient and growing the cells in a laboratory. The corrected copy of the gene is introduced and allowed to penetrate the cells’ DNA before being injected back into the body. Gene transfers can also be done directly inside the patient’s body (in vivo).
Gene Therapy - MayoClinic.com
Gene therapy — Overview covers definition, risk, results of this experimental procedure.
http://www.mayoclinic.com/health/gene-therapy/MY00105
The Journal Of Gene Medicine - Wiley Online Library
Publishes articles on the science of gene transfer and its clinical applications and is the official journal of the European Society of Gene Therapy.
http://www3.interscience.wiley.com/journal/10009391/home

Extractions: document.documentElement.className = "js_en"; Skip to Main Content Home Help LOGIN Enter e-mail address Enter password REMEMBER ME Edited by: Shigetaka Asano, Olivier Danos, Kay Davies, Pierre Lehn, Richard Mulligan Impact Factor: 2.968 Online ISSN: See all The Review More Resources The Database Virtual Issues The Journal of Gene Medicine will be
Gene Therapy Essays And Articles At ENotes
Gene Therapy essays, articles, and viewpoints Gene therapy is based on the concept that genetic disorders and acquired diseases can be treated by replacing abnormal or absent genes
http://www.enotes.com/gene-therapy-article
Gene Therapy - Biotechnology - Science And Research
Describes gene therapy and its applications in treating genetic diseases
http://www.hc-sc.gc.ca/sr-sr/biotech/about-apropos/gen_therap-eng.php
Www.gtmb.org
Free access online journal that publishes articles and reviews relating to the clinical applications of molecular biology.
http://www.gtmb.org/
Gene Therapy — PNAS
Mark A. Kay *, †, Dexi Liu ‡, and Peter M. Hoogerbrugge * Division of Medical Genetics, Department of Medicine, University
http://www.pnas.org/content/94/24/12744.full

Extractions: var callbackToken='511DE4A3D26073F'; PNAS Proceedings of the National Academy of Sciences of the United States of America Skip to main page content Mark A. Kay Dexi Liu , and Peter M. Hoogerbrugge Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA 98195; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261; and Department of Pediatrics, University of Leiden, Leiden, The Netherlands Next Section In recent years, there have been a number of technological breakthroughs that have allowed for clinical trials in gene therapy to be initiated. In combination with the genome initiative, the potential for new therapeutics is limitless. Although an enormous amount of information has been obtained in a relatively short period of time, gene therapy is not yet ready for wide-scale practice. Some of the successes and obstacles that remain are summarized in this report. Previous Section Next Section Gene therapy can be defined as the introduction of nucleic acids into cells for the purpose of altering the course of a medical condition or disease. In general, with some exceptions, the nucleic acids are DNA molecules encoding gene products or proteins. The original ideas were directed toward treating monogenic (single-gene) disorders, but it has become clear that the gene can be considered a new pharmaceutical agent for treating many types of diseases. Over the last 20 years, the initial thoughts of gene therapy have been transformed into reality with more than 175 clinical trials and 2,000 patients already treated (
Human Gene Therapy
Publishes scientific papers on original investigations into the transfer and expression of genes in mammals, including humans. Subscription based.
http://www.liebertpub.com/Products/Product.aspx?pid=19
Gene Therapy I
Disease Genetic defect; hemophilia A absence of clotting factor VIII cystic fibrosis defective chloride channel protein muscular dystrophy defective muscle protein
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/G/GeneTherapy.html

Extractions: Index to this page Gene Therapy: requirements Target Cells ... Adenovirus Vectors Gene Therapy I Many human diseases are caused by defective genes. A few common examples: Disease Genetic defect hemophilia A absence of clotting factor VIII cystic fibrosis defective chloride channel protein muscular dystrophy defective muscle protein (dystrophin) sickle-cell disease defective beta globin hemophilia B absence of clotting factor IX severe combined immunodeficiency (SCID) any one of several genes fail to make a protein essential for T and B cell function All of these diseases are caused by a defect at a single gene locus . (The inheritance is recessive so both the maternal and paternal copies of the gene must be defective.) Is there any hope of introducing functioning genes into these patients to correct their disorder? Probably. Other diseases, also have a genetic basis, but it appears that several genes must act in concert to produce the disease phenotype . The prospects of gene therapy in these cases seems far more remote. SCID is a disease in which the patient has neither It is a disease of young children because, until recently, the absence of an immune system left them prey to infections that ultimately killed them.
Oxford BioMedica
Focuses on developing gene transfer technologies for human gene therapy, gene-based immunotherapy, and gene-based drug discovery for cancer, AIDS, neurodegenerative and cardiovascular disease.
http://www.oxfordbiomedica.co.uk/
GENE THERAPY. - Free Online Library
Free Online Library GENE THERAPY. by The Exceptional Parent ; Consumer news, advice, product reviews Education Family and marriage Gene therapy Evaluation Ornithine
http://www.thefreelibrary.com/GENE THERAPY-a060875635

Extractions: See over-the-counter market (OTC). ) died. His deaththe first that could be directly linked to gene therapyelectrified the scientific community and triggered a national debate that will have a powerful impact on the future of gene therapy experiments and how they are approved and monitored. These are profound and important questions left unanswered, but for Jesse Gelsinger Jesse Gelsinger (June 18 1981 - September 17 1999) was the first person publicly identified as having died in a clinical trial for gene therapy. He was 18 years old. Gelsinger suffered from ornithine transcarbamylase deficiency, an X-linked genetic disease of the liver, whose
KonsoleH :: Login
Focused on developing gene therapies for lipoprotein lipase disorder, inflammatory bowel disease and neuroregeneration. Also provides contract development and manufacturing of gene and cell-based products in their GMP facility.
http://www.amtbv.com/

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